Affinage

RNF10

E3 ubiquitin-protein ligase RNF10 · UniProt Q8N5U6

Length
811 aa
Mass
89.9 kDa
Annotated
2026-04-28
38 papers in source corpus 18 papers cited in narrative 18 extracted findings

Mechanistic narrative

Synthesis pass · prose summary of the discoveries below

RNF10 is a RING-domain E3 ubiquitin ligase that functions as a central effector of ribosome quality control and additionally serves as a transcriptional regulator in neurons and other cell types. In the initiation ribosome quality control (iRQC) pathway, RNF10 monoubiquitylates 40S ribosomal proteins uS3/RPS3 and uS5/RPS2 on stalled or mRNA-engaged ribosomes, promoting 40S subunit dissociation, half-mer resolution, and selective 40S degradation via RIOK3-mediated 18S nonfunctional rRNA decay within a GCN2-dependent integrated stress response; USP10 acts as the counteracting deubiquitylase, and RNF10 protein levels are dynamically coupled to 40S subunit abundance (PMID:34469731, PMID:34348161, PMID:39947182, PMID:39947183, PMID:39609413). In neurons, RNF10 resides at excitatory synapses in complex with the NMDAR GluN2A subunit and, upon synaptic activation, undergoes PKC-dependent Ser31 phosphorylation, importin-mediated nuclear translocation, and regulation of transcriptional programs required for LTP maintenance and dendritic spine remodeling (PMID:26977767, PMID:31069631). Independent of its ligase activity, RNF10 functions as a transcriptional activator of MAG in Schwann cells to promote myelination, interacts with MEOX2 to co-activate p21-dependent cell cycle exit during neuronal differentiation, and represses Rbpjk transcription in vascular smooth muscle cells to inhibit osteogenic transdifferentiation (PMID:18941509, PMID:16335786, PMID:23526782, PMID:41988714).

Mechanistic history

Synthesis pass · year-by-year structured walk · 12 steps
  1. 2005 High

    Identification of RNF10 as a physical partner of the homeodomain transcription factor MEOX2 established RNF10's first known protein interaction and linked it to p21-dependent transcriptional regulation, raising the question of whether RNF10 functions beyond canonical E3 ligase activity.

    Evidence Yeast two-hybrid, co-IP, in vitro pull-down, and p21 promoter reporter assay in mammalian cells

    PMID:16335786

    Open questions at the time
    • RING domain dispensability for MEOX2 binding was shown but the RING domain's catalytic role was not tested in this context
    • endogenous co-expression and physiological relevance not established
  2. 2008 High

    Discovery that RNF10 directly binds a cis-element upstream of the MAG gene and activates MAG transcription in Schwann cells established RNF10 as a bona fide transcriptional activator controlling peripheral myelination.

    Evidence Yeast one-hybrid screen, luciferase reporters, siRNA knockdown, and Schwann cell–DRG neuron myelination co-culture

    PMID:18941509

    Open questions at the time
    • Mechanism by which a RING-domain protein binds DNA and activates transcription not resolved
    • relationship between ubiquitin ligase activity and transcriptional function not tested
  3. 2013 Medium

    Demonstration that RNF10 is required for retinoic acid-induced neuronal differentiation and cell cycle exit through p21 upregulation connected RNF10's transcriptional co-activator role with MEOX2 to a defined developmental process.

    Evidence siRNA knockdown in P19 cells, cell cycle profiling, p21 rescue experiment

    PMID:23526782

    Open questions at the time
    • Study performed in a single cell line (P19)
    • direct transcriptional mechanism on p21 promoter not dissected
    • whether RNF10 E3 activity is involved in cell cycle regulation unclear
  4. 2016 High

    Identification of RNF10 as an activity-dependent synaptonuclear messenger that translocates from NMDAR/GluN2A complexes to the nucleus upon LTP induction revealed a non-canonical signaling function for an E3 ligase in synaptic plasticity.

    Evidence Co-IP with GluN2A, live-cell imaging, importin inhibition, siRNA knockdown with LTP electrophysiology and spine morphology readouts in neurons

    PMID:26977767

    Open questions at the time
    • Nuclear transcriptional targets mediating LTP maintenance not identified
    • whether ubiquitin ligase activity is required for the synaptic function not tested
  5. 2019 High

    Pinpointing PKC-dependent phosphorylation of Ser31 as the molecular switch controlling RNF10 detachment from GluN2A and nuclear import resolved the activation mechanism of the synaptonuclear signaling pathway.

    Evidence Phosphomimetic/phosphodead mutants, live-cell imaging, spine morphometry, CREB reporter assays in neurons

    PMID:31069631

    Open questions at the time
    • Identity of the specific PKC isoform responsible not determined
    • downstream nuclear gene targets of RNF10 still undefined
  6. 2021 High

    Two independent studies identified RNF10 as the E3 ligase that monoubiquitylates 40S ribosomal proteins uS3 and uS5 during ribosome-associated quality control, with USP10 as the antagonizing deubiquitylase, establishing the initiation RQC (iRQC) pathway and redefining RNF10's primary molecular function.

    Evidence Genetic screens, quantitative proteomics, PAR-CLIP, ribosome fractionation, knockout/knockdown with ribosome degradation and translation reporter assays

    PMID:34348161 PMID:34469731

    Open questions at the time
    • How RNF10 is recruited to stalled ribosomes at a structural level remained unknown
    • downstream fate of ubiquitinated 40S subunits not fully resolved
  7. 2021 Medium

    RNF10 knockdown in macrophages enhanced NF-κB and IRF3 signaling, suggesting a negative regulatory role for RNF10 in innate immune activation, though the direct ubiquitin substrates mediating this effect were not identified.

    Evidence siRNA knockdown in macrophages, pathway reporter assays, cytokine quantification, bacterial clearance assay

    PMID:33249776

    Open questions at the time
    • Ubiquitin substrates mediating immune suppression not identified
    • not independently replicated
    • unclear if this reflects ribosome QC effects on cytokine translation or a direct signaling role
  8. 2024 High

    RNF10 ubiquitylation of uS3 was shown to antagonize ribosomal half-mer formation and RNF10 protein levels were found to be dynamically coupled to 40S abundance, revealing a homeostatic feedback mechanism that tunes iRQC to ribosomal subunit stoichiometry.

    Evidence Ribosome fractionation, half-mer analysis, RPS/RPL knockdowns, proteasome inhibition in human cells

    PMID:39609413

    Open questions at the time
    • Proteasomal pathway responsible for RNF10 degradation when 40S levels drop not characterized
    • structural basis of RNF10's preference for stalled vs. translating 40S not resolved
  9. 2024 Medium

    Conservation of RNF10-mediated 40S ubiquitylation was demonstrated in Drosophila, where RNF10 and CNOT4 ubiquitylate eS7/RPS7 upstream of the deubiquitylase OTUD6, extending the pathway to an additional substrate and linking it to alkylation stress responses.

    Evidence Coimmunoprecipitation, OTUD6 catalytic-dead enrichment, genetic epistasis in Drosophila

    PMID:39127721

    Open questions at the time
    • Relative contributions of RNF10 vs. CNOT4 on eS7 not separated
    • mammalian eS7 ubiquitylation by RNF10 not confirmed
  10. 2025 High

    The downstream effector RIOK3 was identified as the factor that recognizes RNF10-ubiquitylated 40S subunits via a ubiquitin-interacting motif (cryo-EM resolved) and executes 3′-to-5′ 18S rRNA decay, completing the mechanistic pathway from RNF10-mediated ubiquitylation to selective 40S destruction within a GCN2-dependent integrated stress response.

    Evidence Genome-wide CRISPR epistasis screens, selective ribosome profiling, cryo-EM of RIOK3–ubiquitylated 40S complex, 18S rRNA decay assays, amino acid starvation

    PMID:39947182 PMID:39947183 PMID:40022732

    Open questions at the time
    • How GCN2 activation feeds back to increase RNF10 recruitment to ribosomes not structurally resolved
    • nuclease(s) executing 18S rRNA degradation downstream of RIOK3 not identified
  11. 2025 Medium

    LTN1, the E3 ligase of the canonical 60S-associated RQC pathway, was found to suppress RNF10 expression in a RING-domain-dependent manner, revealing regulatory crosstalk between the two branches of ribosome quality control.

    Evidence Knockout mouse and human cell lines, western blotting, RING domain mutant analysis

    PMID:41451945

    Open questions at the time
    • Whether LTN1 directly ubiquitylates RNF10 or acts indirectly not determined
    • physiological contexts where LTN1–RNF10 crosstalk is rate-limiting not defined
  12. 2025 High

    Nuclear RNF10 was shown to transcriptionally repress Rbpjk in vascular smooth muscle cells through a non-ubiquitin-ligase mechanism, protecting against vascular calcification in chronic kidney disease, expanding RNF10's transcriptional regulatory repertoire to a new tissue and disease context.

    Evidence Rnf10 knock-in rats, RNA-seq, ChIP-seq, ChIP-qPCR, luciferase reporters, Rbpjk epistasis experiments, proteasome inhibition

    PMID:41988714

    Open questions at the time
    • DNA-binding domain or cofactor enabling RNF10 transcriptional repression of Rbpjk not identified
    • relationship between RNF10's ribosome QC role and its nuclear transcriptional function in VSMCs not addressed

Open questions

Synthesis pass · forward-looking unresolved questions
  • A unifying model explaining how RNF10 partitions between its cytoplasmic ribosome quality control function and its nuclear transcriptional roles, and how these dual activities are coordinated in the same cell, remains unresolved.
  • No structural model of RNF10 on the ribosome exists
  • mechanism of RNF10 DNA binding (direct vs. cofactor-dependent) is unknown
  • tissue-specific regulation of RNF10's ligase vs. transcriptional functions not systematically characterized

Mechanism profile

Synthesis pass · controlled-vocabulary classification · explore literature graph →
Molecular activity
GO:0140096 catalytic activity, acting on a protein 7 GO:0140110 transcription regulator activity 4 GO:0003677 DNA binding 1 GO:0003723 RNA binding 1
Localization
GO:0005840 ribosome 6 GO:0005634 nucleus 4 GO:0005829 cytosol 2 GO:0005886 plasma membrane 1
Pathway
R-HSA-392499 Metabolism of proteins 7 R-HSA-74160 Gene expression (Transcription) 3 R-HSA-112316 Neuronal System 2 R-HSA-1266738 Developmental Biology 2 R-HSA-8953854 Metabolism of RNA 2 R-HSA-8953897 Cellular responses to stimuli 2
Partners
GRIN2ALTN1MEOX2RIOK3RPS2RPS3USP10

Evidence

Reading pass · 18 per-paper findings extracted from the source corpus
Year Finding Method Journal Conf PMIDs
2021 RNF10 is the E3 ubiquitin ligase responsible for site-specific monoubiquitylation of 40S ribosomal proteins uS3 (RPS3) and uS5 (RPS2) during ribosome-associated quality control (RQC). USP10 is the counteracting deubiquitylase. Prolonged uS3/uS5 ubiquitylation leads to selective 40S (but not 60S) ribosomal protein degradation independent of canonical autophagy. This pathway, termed initiation RQC (iRQC), is triggered when scanning or elongating ribosomes are blocked from progressing past the start codon. Genetic screens, quantitative proteomics, knockdown/knockout with ribosome degradation readouts, translation reporter assays Cell reports High 34469731
2021 RNF10 monoubiquitinates RPS2/uS5 and RPS3/uS3 on ribosomes stalled in translation; overexpression of RNF10 phenocopies USP10 knockout by increasing 40S subunit degradation. PAR-CLIP showed RNF10 crosslinks to mRNAs, tRNAs, and 18S rRNA, indicating direct recruitment to stalled ribosomes. ZNF598-independent translation initiation and elongation impairment also contributes to RNF10-mediated ubiquitination. Overexpression/knockout cell lines, PAR-CLIP, ribosome fractionation, ubiquitination assays Cell reports High 34348161
2025 Mammalian 18S nonfunctional rRNA decay (NRD) proceeds through a GCN2-RNF10-RIOK3 axis: nonfunctional 18S rRNA induces translational arrest at start sites, activating GCN2 (integrated stress response), which limits translation initiation; RNF10-mediated ubiquitination of 40S proteins then promotes 40S ribosomal protein turnover and 18S rRNA decay, with RIOK3 binding ubiquitinated 40S subunits to facilitate 18S rRNA degradation. Genome-wide CRISPR genetic interaction screens, selective ribosome profiling, biochemical ISR activation assays, 18S rRNA decay assays Molecular cell High 39947182
2025 RIOK3 specifically recognizes RNF10-ubiquitylated 40S ribosomes through a unique ubiquitin-interacting motif (visualized by cryo-EM), and mediates progressive 3'-to-5' decay of 18S rRNA in the ubiquitylated 40S subunit. Starvation induces selective depletion of 40S ribosomes via RNF10 ubiquitylation followed by RIOK3-dependent degradation. Cryo-EM structure of RIOK3–ubiquitylated 40S complex, genetic knockouts, ribosome degradation assays Molecular cell High 39947183
2025 Disruption of 60S biogenesis triggers iRQC activation and 40S decay via RNF10-mediated ubiquitylation of uS3/uS5; depletion of the scanning helicase eIF4A1 impairs 40S ubiquitylation, indicating mRNA engagement is required for iRQC. Amino acid starvation also stimulates iRQC-dependent 40S decay. RIOK3 interacts with ubiquitylated 40S subunits to mediate degradation, and both RNF10 and RIOK3 protein levels increase upon iRQC activation (feedforward mechanism). Genetic knockdowns of 60S/40S biogenesis factors, eIF4A1 depletion, amino acid starvation assays, co-immunoprecipitation of RIOK3 with ubiquitylated 40S Cell reports High 40022732
2024 RNF10-mediated monoubiquitination of RPS3/uS3 antagonizes ribosomal half-mer formation by promoting dissociation of 40S subunits from ribosomes stalled during both translation elongation and aberrant initiation. RNF10 protein levels are coupled to 40S subunit abundance: knockdown of RPS proteins leads to proteasomal degradation of RNF10, whereas knockdown of RPL proteins causes accumulation of stalled initiating 40S subunits and increased RNF10 levels. Ribosome fractionation, half-mer analysis, RPS/RPL knockdowns, proteasome inhibition, ubiquitination assays Nature communications High 39609413
2025 The E3 ubiquitin ligase LTN1 suppresses RNF10 expression in a manner dependent on LTN1's RING domain, revealing crosstalk between RQC-associated E3 ligases as a mechanism coordinating translational surveillance pathways. Knockout mouse and human cell lines, western blotting, RING domain mutant analysis FEBS letters Medium 41451945
2016 RNF10 is a synaptonuclear messenger enriched at excitatory synapses where it associates with the GluN2A subunit of NMDA receptors. Activation of synaptic GluN2A-containing NMDARs and LTP induction cause RNF10 translocation from dendritic segments and spines to the nucleus via importin-dependent long-distance transport. RNF10 silencing prevents LTP maintenance and LTP-dependent structural modifications of dendritic spines. Co-immunoprecipitation with GluN2A, live-cell imaging, importin inhibition, siRNA knockdown with LTP electrophysiology and spine morphology readouts eLife High 26977767
2019 PKC-dependent phosphorylation of RNF10 at Ser31 is required for RNF10 detachment from the NMDA receptor GluN2A subunit and subsequent nuclear trafficking. Preventing Ser31 phosphorylation decreases spine density, neuronal branching, and CREB signaling; mimicking stable Ser31 phosphorylation has opposite effects. Phosphomimetic/phosphodead mutants, live-cell imaging, dendritic spine morphometry, CREB reporter assays Molecular neurobiology High 31069631
2008 RNF10 binds to a cis-acting element ~160 bp upstream of the MAG transcription start site and acts as a transcriptional activator of the myelin-associated glycoprotein (MAG) gene in Schwann cells. RNF10 knockdown reduces endogenous MAG mRNA and protein; retroviral RNF10 siRNA in Schwann cell–DRG neuron co-cultures inhibits myelin formation. Yeast one-hybrid screen, luciferase reporter assay, siRNA knockdown, retroviral transduction, Schwann cell–DRG neuron myelination co-culture PloS one High 18941509
2005 RNF10 physically interacts with the transcription factor MEOX2 via a central region of MEOX2 (amino acids 101–185); the RING finger domain of RNF10 is not required for MEOX2 binding. RNF10 co-expression enhances MEOX2-mediated activation of the p21WAF1 promoter. Yeast two-hybrid screen, in vitro pull-down, co-immunoprecipitation in mammalian cells, deletion mapping, luciferase reporter assay Molecular and cellular biochemistry High 16335786
2013 RNF10 expression increases upon retinoic acid-induced neuronal differentiation of P19 cells; RNF10 knockdown impairs neuronal differentiation and prevents cell cycle arrest after RA treatment. RNF10 regulates cell cycle exit through upregulation of p21 (but not p27 or p57), and ectopic p21 partially rescues the differentiation defect caused by RNF10 depletion. siRNA knockdown, BrdU incorporation, flow cytometry cell cycle profiling, neuronal marker western blots, p21 rescue experiment Journal of cellular biochemistry Medium 23526782
2013 RNF10 is identified as a target of S-nitrosylation; eight ubiquitin E3 ligases including RNF10 were found to be potentially S-nitrosylated, suggesting NO-mediated regulation of RNF10's ubiquitin ligase activity. High-density protein microarray with S-nitrosylation-specific labeling and affinity capture; mass spectrometry identification of modified cysteines Molecular & cellular proteomics Low 24105792
2024 In Drosophila, the E3 ligases CNOT4 and RNF10 function upstream of the deubiquitinase OTUD6 to regulate ubiquitination of RPS7/eS7 on the free 40S ribosome, modulating global protein translation and the response to alkylation stress. Coimmunoprecipitation, enrichment of monoubiquitinated proteins from catalytically inactive OTUD6 Drosophila, genetic epistasis Nature communications Medium 39127721
2021 RNF10 knockdown in macrophages enhances both NF-κB and IRF3 signaling pathways, leading to increased proinflammatory cytokines and type I interferons, and promoting clearance of Listeria monocytogenes, indicating RNF10 acts as a negative regulator of innate immune signaling in macrophages. siRNA knockdown in macrophages, NF-κB/IRF3 pathway reporter assays, cytokine/interferon quantification, bacterial clearance assay FEBS open bio Medium 33249776
2026 In the context of vascular calcification in chronic kidney disease, nuclear RNF10 negatively regulates Rbpjk expression in VSMCs through a transcriptional (non-ubiquitin-ligase) mechanism. Proteasome inhibition does not impair RNF10's anticalcific activity. Viral Rbpjk overexpression reverses RNF10's protective effects, while Rbpjk knockdown reduces osteogenic markers, defining an RNF10-Rbpjk regulatory axis. Rnf10 knock-in rats, RNF10 overexpression in VSMCs, RNA-seq, ChIP-seq, ChIP-qPCR, luciferase reporter assays, gain- and loss-of-function for Rbpjk in vivo and in vitro, proteasome inhibition Arteriosclerosis, thrombosis, and vascular biology High 41988714
2007 RNF10 interacts with the tumor suppressor RASSF1C in a yeast two-hybrid screen confirmed by in vitro pull-down of bacterially expressed proteins, placing RNF10 within a nuclear interactome network that includes hampin/MSL1 and associated chromatin regulators. Yeast two-hybrid library screen, in vitro pull-down with bacterially expressed proteins Biochemical and biophysical research communications Low 17335777
2011 RNF10 interacts with HSV-1 tegument protein VP22; co-expression of VP22 with RNF10 relocates RNF10 from its normal subcellular distribution pattern, indicating VP22 modulates RNF10 localization. Yeast two-hybrid, fluorescent protein tagging and co-expression imaging Archives of virology Low 21424732

Source papers

Stage 0 corpus · 38 papers · ranked by NIH iCite citations
Year Title Journal Citations PMID
2021 iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation. Cell reports 55 34469731
2020 Putative regulators for the continuum of erythroid differentiation revealed by single-cell transcriptome of human BM and UCB cells. Proceedings of the National Academy of Sciences of the United States of America 52 32457162
2013 Protein microarray characterization of the S-nitrosoproteome. Molecular & cellular proteomics : MCP 50 24105792
2021 The E3 ubiquitin ligase RNF10 modifies 40S ribosomal subunits of ribosomes compromised in translation. Cell reports 45 34348161
2016 Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus. eLife 38 26977767
2010 Genomics and proteomics approaches to the study of cancer-stroma interactions. BMC medical genomics 34 20441585
2018 Synapse-to-nucleus communication: from developmental disorders to Alzheimer's disease. Current opinion in neurobiology 33 29316492
2005 Characterization of Mesenchyme Homeobox 2 (MEOX2) transcription factor binding to RING finger protein 10. Molecular and cellular biochemistry 22 16335786
2008 A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells. PloS one 19 18941509
2025 The integrated stress response regulates 18S nonfunctional rRNA decay in mammals. Molecular cell 17 39947182
2023 A deep transcriptome meta-analysis reveals sex differences in multiple sclerosis. Neurobiology of disease 17 37023829
2013 RING finger protein 10 regulates retinoic acid-induced neuronal differentiation and the cell cycle exit of P19 embryonic carcinoma cells. Journal of cellular biochemistry 17 23526782
2007 Characterization of hampin/MSL1 as a node in the nuclear interactome. Biochemical and biophysical research communications 15 17335777
2025 RIOK3 mediates the degradation of 40S ribosomes. Molecular cell 14 39947183
2019 The Synaptonuclear Messenger RNF10 Acts as an Architect of Neuronal Morphology. Molecular neurobiology 14 31069631
2025 RNF10 and RIOK3 facilitate 40S ribosomal subunit degradation upon 60S biogenesis disruption or amino acid starvation. Cell reports 11 40022732
2024 E3 ubiquitin ligase RNF10 promotes dissociation of stalled ribosomes and responds to ribosomal subunit imbalance. Nature communications 9 39609413
2025 An in-silico pan-cancer bulk and single-cell profiling of transcription factors in protein autoubiquitination. Discover oncology 8 40591126
2018 RING finger protein 10 attenuates vascular restenosis by inhibiting vascular smooth muscle cell hyperproliferation in vivo and vitro. IUBMB life 8 30597731
2011 Host cell targets of tegument protein VP22 of herpes simplex virus 1. Archives of virology 8 21424732
2019 RING finger protein 10 is a potential drug target for diabetic vascular complications. Molecular medicine reports 7 31173254
2023 An epitope encoded by uORF of RNF10 elicits a therapeutic anti-tumor immune response. Molecular therapy oncolytics 6 38020063
2018 RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo. Life sciences 5 29723537
2024 OTUD6 deubiquitination of RPS7/eS7 on the free 40 S ribosome regulates global protein translation and stress. Nature communications 4 39127721
2024 The integrated stress response regulates 18S nonfunctional rRNA decay in mammals. bioRxiv : the preprint server for biology 3 39211161
2021 Reduced RING finger protein 10 expression in macrophages is associated with aging-related inflammation. FEBS open bio 3 33249776
2005 A new mutation in the timing of autogamy in Paramecium tetraurelia. Mechanisms of ageing and development 3 15888330
2025 Employing Expression-Matched Controls Enables High-Confidence Proximity-Based Interactome Classification. Molecular & cellular proteomics : MCP 2 40441440
2023 RING Finger Protein 10 Regulates AP-1/Meox2 to Mediate Pirarubicin-Induced Cardiomyocyte Apoptosis. Oxidative medicine and cellular longevity 2 36713029
2023 Screening the optimal housekeeping genes (HKGs) of placenta tissues by RNA-sequence and qRT-PCR throughout gestation in goat (Capra Hircus). Gene 2 37972698
2022 CircRNA RNF10 inhibits tumorigenicity by targeting miR-942-5p/GOLIM4 axis in breast cancer. Environmental and molecular mutagenesis 2 36054164
2025 Genomic Exploration of Selection Signatures Linked to Reproductive Traits in Locally Adapted Indicine, Taurine and Crossbred Cattle of India. Reproduction in domestic animals = Zuchthygiene 1 40631534
2023 Ring finger protein 10 improves pirarubicin-induced cardiac inflammation by regulating the AP-1/Meox2 signaling pathway. Toxicology and applied pharmacology 1 36740146
2026 E3 Ubiquitin Ligase RNF10 Negatively Regulates Rbpjk Expression During Vascular Calcification in Chronic Kidney Disease. Arteriosclerosis, thrombosis, and vascular biology 0 41988714
2025 Genomic scan of selective sweeps in an alpaca population subjected to directional selection for fibre quality traits. Animal : an international journal of animal bioscience 0 41161070
2025 Ring finger protein 10 is atherosclerosis protective and modulates macrophage polarization. Experimental animals 0 41339005
2025 Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10. FEBS letters 0 41451945
2006 [Cloning to rule out 10 candidate genes located in chromosome 12q24 for Charcot-Marie-Tooth disease type 2L]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 0 16604494