Affinage

RPL13

Large ribosomal subunit protein eL13 · UniProt P26373

Round 2 corrected
Length
211 aa
Mass
24.3 kDa
Annotated
2026-04-28
69 papers in source corpus 13 papers cited in narrative 13 extracted findings

Mechanistic narrative

Synthesis pass · prose summary of the discoveries below

RPL13 (eL13) is an integral protein of the 60S large ribosomal subunit that functions in canonical mRNA translation and possesses extraribosomal regulatory activities. Structurally resolved at near-atomic resolution within the human 80S ribosome (PMID:25901680), RPL13 is required for proper 60S–80S subunit dynamics and global translation, as patient-derived missense variants alter the 60S:80S ratio and attenuate protein synthesis (PMID:32916022). Beyond its core ribosomal role, RPL13 selectively promotes viral IRES-driven translation by cooperating with DDX3 and eIF3 subunits to facilitate 80S assembly on viral mRNAs (PMID:31619563), and it modulates NF-κB/IFN-β innate immune signaling (PMID:34093518). Pathogenic variants in RPL13 — clustering in an RNA-binding motif — cause spondyloepimetaphyseal dysplasia with severe short stature, establishing it as a ribosomopathy gene essential for skeletal and cardiac development (PMID:31630789, PMID:31625562).

Mechanistic history

Synthesis pass · year-by-year structured walk · 12 steps
  1. 1976 High

    Identification of RPL13 as a bona fide structural component of the large ribosomal subunit established its primary molecular identity and set the stage for all subsequent functional studies.

    Evidence Biochemical purification from rat liver 60S ribosomes with SDS-PAGE and amino acid composition analysis

    PMID:1002715

    Open questions at the time
    • No functional assay performed
    • Human homolog not yet characterized
  2. 1994 High

    Determination of the full primary structure of RPL13 (210 aa, 24 kDa) and its multi-copy gene organization provided the molecular framework for subsequent genetic and structural studies.

    Evidence cDNA sequencing, Southern and Northern blotting in rat

    PMID:8198561

    Open questions at the time
    • No structure–function analysis
    • Human ortholog sequence not directly determined in this study
  3. 2003 High

    Discovery that the paralog RPL13A is phosphorylated and released from 60S subunits upon IFN-γ stimulation to silence ceruloplasmin mRNA via GAIT-element binding established the paradigm that large-subunit ribosomal proteins can have extraribosomal translational regulatory functions.

    Evidence Genetic screen, in vitro translation inhibition, phosphorylation assay, ribosome fractionation, RNA-binding assay

    PMID:14567916

    Open questions at the time
    • Whether RPL13 itself (not just L13a) undergoes analogous release and GAIT-mediated regulation was not tested
    • Mechanism of phosphorylation-triggered release from ribosome not resolved
  4. 2013 High

    Cryo-EM structures of metazoan 80S ribosomes placed RPL13 within its three-dimensional architectural context, revealing its position relative to metazoan-specific rRNA expansions and neighboring ribosomal proteins.

    Evidence High-resolution cryo-EM of Drosophila and human 80S ribosomes

    PMID:23636399

    Open questions at the time
    • Specific protein–protein and protein–rRNA contacts of RPL13 not fully resolved at this resolution
    • No mutagenesis to test functional importance of structural contacts
  5. 2015 High

    Near-atomic resolution structure of the human 80S ribosome provided detailed side-chain-level information for RPL13, enabling precise mapping of disease-associated variants onto the structure.

    Evidence 3.6 Å single-particle cryo-EM of the human 80S ribosome

    PMID:25901680

    Open questions at the time
    • Functional consequences of specific RPL13 structural contacts not tested experimentally
  6. 2006 Medium

    Knockdown experiments revealed that RPL13 contributes to cell cycle progression and chemoresistance in gastrointestinal cancer cells, suggesting functions beyond constitutive translation.

    Evidence siRNA knockdown, flow cytometry cell cycle analysis, growth assays in human cancer cell lines

    PMID:16786168

    Open questions at the time
    • Whether the cell cycle phenotype is due to global translation impairment versus a specific extraribosomal mechanism is unresolved
    • No rescue experiment performed
    • Single cancer context
  7. 2019 High

    Identification of de novo RPL13 variants in patients with spondyloepimetaphyseal dysplasia directly linked RPL13 to a Mendelian skeletal disorder, and altered ribosome profiles in patient cells established it as a ribosomopathy gene.

    Evidence Patient-derived cell studies, sucrose gradient ribosome profiling, erythroid culture, immunohistochemistry of mouse growth plates, splice analysis

    PMID:31630789

    Open questions at the time
    • Precise mechanism by which mutant eL13 alters translation dynamics (ribosome stalling vs. assembly defect) not determined
    • Tissue-specific vulnerability of cartilage/bone not mechanistically explained
  8. 2019 Medium

    RPL13 knockdown in human iPSC-derived cardiac progenitors and Drosophila heart-specific RNAi demonstrated a requirement for RPL13 in cardiomyocyte differentiation and cardiac morphogenesis across species.

    Evidence siRNA knockdown in human iPSC-derived cardiac progenitors, heart-specific RNAi in Drosophila

    PMID:31625562

    Open questions at the time
    • Whether the cardiac phenotype is translation-dependent or involves an extraribosomal activity of RPL13 is unknown
    • No rescue experiment with wild-type RPL13
  9. 2020 Medium

    RPL13 was shown to selectively regulate viral IRES-driven translation in cooperation with DDX3 and eIF3 subunits, demonstrating that RPL13 promotes alternative translation initiation pathways distinct from its role in cap-dependent translation.

    Evidence siRNA knockdown, co-immunoprecipitation, IRES reporter assays, ribosome assembly assays, RNA immunoprecipitation

    PMID:31619563

    Open questions at the time
    • Whether RPL13 acts as a free protein or within the 60S subunit during IRES-mediated initiation is unclear
    • Structural basis of RPL13–DDX3 cooperativity not resolved
    • Findings from a single lab
  10. 2020 High

    Functional and structural characterization of additional SEMD-RPL13 patient variants confirmed reduced eL13–eL28 colocalization, elevated 60S:80S ratio, and attenuated global translation; CRISPR rpl13 mutant zebrafish recapitulated cartilage defects, validating the causal link in a vertebrate model.

    Evidence Patient-derived fibroblasts, immunofluorescence colocalization, sucrose gradient profiling, CRISPR-Cas9 zebrafish knockout

    PMID:32916022

    Open questions at the time
    • Whether the skeletal phenotype arises from global translation deficiency or loss of specific mRNA targets is unresolved
    • Zebrafish model not complemented with human RPL13 rescue
  11. 2021 Medium

    RPL13 was found to activate NF-κB and IFN-β signaling and promote antiviral cytokine secretion; FMDV 3C protease cleaves RPL13 to evade this innate immune function, connecting RPL13 to host antiviral defense.

    Evidence Overexpression and knockdown, NF-κB/IFN-β luciferase reporters, ELISA for IFN-β and IL-6, co-immunoprecipitation with 3Cpro

    PMID:34093518

    Open questions at the time
    • Whether RPL13-mediated NF-κB activation occurs as a free protein or requires ribosome-associated context is not known
    • Signaling intermediaries between RPL13 and NF-κB not identified
    • Single lab, single viral system
  12. 2023 Low

    Mapping of all known SEMD-RPL13 variants to a single RNA-binding motif (intron 5/exon 6) raised the hypothesis that disruption of extraribosomal mRNA-binding — rather than ribosome assembly — is the primary pathogenic mechanism, since pre-rRNA processing was unaffected.

    Evidence Structural variant mapping, splicing assays, clinical characterization

    PMID:37993442

    Open questions at the time
    • Direct experimental evidence that SEMD variants impair specific mRNA binding by RPL13 is lacking
    • No identification of the putative target mRNAs
    • Pre-rRNA processing assay performed in limited cell types

Open questions

Synthesis pass · forward-looking unresolved questions
  • The central unresolved question is whether the tissue-specific pathology of RPL13 ribosomopathy arises from global translational insufficiency, selective translational dysregulation of specific mRNA targets, or loss of extraribosomal functions such as IRES-mediated translation or NF-κB signaling.
  • No ribosome profiling (Ribo-seq) of RPL13-mutant cells to identify differentially translated mRNAs
  • No structural model of disease-variant RPL13 within the 60S subunit
  • Extraribosomal interactome of RPL13 not systematically defined

Mechanism profile

Synthesis pass · controlled-vocabulary classification · explore literature graph →
Molecular activity
GO:0005198 structural molecule activity 3 GO:0003723 RNA binding 2 GO:0045182 translation regulator activity 2
Localization
GO:0005840 ribosome 5 GO:0005829 cytosol 2
Pathway
R-HSA-1643685 Disease 2 R-HSA-168256 Immune System 2
Partners
DDX3EIF3EEIF3JRPL13ARPL28
Complex memberships
60S large ribosomal subunit80S ribosome

Evidence

Reading pass · 13 per-paper findings extracted from the source corpus
Year Finding Method Journal Conf PMIDs
1976 RPL13 (L13) was isolated and purified from the rat liver 60S ribosomal subunit. Its molecular weight was estimated by SDS-PAGE and amino acid composition was determined, establishing it as an integral protein of the large ribosomal subunit. Ion exchange chromatography, gel filtration, SDS-PAGE, amino acid composition analysis The Journal of biological chemistry High 1002715
1994 The primary structure of rat ribosomal protein L13 was determined: it has 210 amino acids (NH2-terminal methionine is removed post-translationally), a molecular weight of 24,094 Da, and is encoded by 8–10 gene copies. The mRNA is ~870 nucleotides in length. cDNA sequencing, Southern blotting, Northern blotting Biochemical and biophysical research communications High 8198561
2003 Human ribosomal protein L13a (RPL13A, a paralog; however this paper specifically identifies L13a as the GAIT factor) is released from the 60S ribosomal subunit upon interferon-gamma stimulation. Released L13a is phosphorylated and binds the GAIT element in the 3'-UTR of ceruloplasmin mRNA to silence its translation, demonstrating that an integral ribosomal protein can serve as a transcript-specific translational repressor. Genetic screen for 3'-UTR binding proteins, in vitro translation inhibition with recombinant protein, phosphorylation assay, ribosome fractionation, RNA-binding assay Cell High 14567916
2006 RPL13 mRNA is up-regulated in human gastrointestinal cancers. siRNA-mediated knockdown of RPL13 in cancer cells causes G1 and G2/M cell cycle arrest and attenuates cell growth, while L13-overexpressing cells exhibit greater chemoresistance to DNA-damaging agents, indicating RPL13 plays a role in cell cycle progression and DNA damage response. siRNA knockdown, cell cycle analysis (flow cytometry), cell growth assays, RT-PCR expression analysis International journal of molecular medicine Medium 16786168
2013 Cryo-EM structures of Drosophila melanogaster and Homo sapiens 80S ribosomes were determined, revealing the structural position and context of RPL13 within the large 60S subunit in the context of metazoan-specific ribosomal RNA and protein layers. High-resolution cryo-electron microscopy Nature High 23636399
2015 Near-atomic (3.6 Å, with some regions at 2.9 Å) cryo-EM structure of the human 80S ribosome was determined, providing detailed structural information about RPL13's position and interactions within the human 60S subunit including atomic details of amino acid side chains. Single-particle cryo-electron microscopy and atomic model building Nature High 25901680
2019 De novo variants in RPL13 (missense and splice variants causing 18-amino acid insertion) cause spondyloepimetaphyseal dysplasia with severe short stature. The insertion-containing protein is stably expressed and incorporated into 60S subunits similarly to wild-type, but erythroid proliferation and ribosome profiles on sucrose gradients are altered, suggesting changed translation dynamics. RPL13 is present at high levels in chondrocytes and osteoblasts in mouse growth plates, implicating it in bone development. Patient-derived cell studies, ribosome profiling on sucrose gradients, erythroid culture proliferation assays, immunohistochemistry of mouse growth plates, RNA splicing analysis American journal of human genetics High 31630789
2019 Knockdown of RPL13 in human iPSC-derived multipotent cardiac progenitor cells reduces proliferation and differentiation of cardiomyocytes while increasing fibroblast numbers. Heart-specific RpL13 knockdown in Drosophila at embryonic stages results in a 'no heart' phenotype, indicating a role in cardiogenesis. siRNA knockdown in human iPSC-derived cardiac progenitors, Drosophila heart-specific RNAi, cardiac phenotyping Human molecular genetics Medium 31625562
2020 RPL13 is a critical regulator of IRES-driven translation of foot-and-mouth disease virus (FMDV), Seneca Valley virus, and classical swine fever virus, but is not essential for global cellular translation. RPL13 cooperates with DEAD box helicase DDX3: DDX3 depletion disrupts RPL13 binding to the FMDV IRES, and RPL13 depletion impairs DDX3's ability to promote IRES-driven translation. Together they support 80S ribosome assembly for viral mRNA translation initiation, and DDX3 affects recruitment of eIF3e and eIF3j to the viral IRES. siRNA knockdown, co-immunoprecipitation, ribosome assembly assays, IRES-driven reporter translation assays, RNA immunoprecipitation Journal of virology Medium 31619563
2020 RPL13 missense variants in patients with SEMD cause reduced colocalization of eL13 with eL28, an increased ratio of 60S subunits to 80S ribosomes, and attenuated global translation in patient-derived dermal fibroblasts. CRISPR-generated rpl13 mutant zebrafish exhibit cartilage deformities, confirming the role of RPL13 in skeletogenesis. These findings establish SEMD-RPL13 as a ribosomopathy with incomplete penetrance and variable expressivity. Patient-derived fibroblast studies, immunofluorescence colocalization, sucrose gradient ribosome profiling, global translation assay, CRISPR-Cas9 zebrafish model Journal of bone and mineral research High 32916022
2021 RPL13 participates in antiviral innate immune response against FMDV. Overexpression of RPL13 promotes NF-κB and IFN-β promoter activation and increases IFN-β and IL-6 secretion, while knockdown has the opposite effect. FMDV 3C protease (3Cpro) interacts with RPL13 and cleaves/reduces RPL13 expression to antagonize its antiviral activity. Overexpression and siRNA knockdown, luciferase reporter assays for NF-κB and IFN-β promoters, ELISA for cytokine secretion, co-immunoprecipitation of 3Cpro with RPL13 Frontiers in immunology Medium 34093518
2023 Structural analysis of SEMD-RPL13 variants, all clustering within intron 5 and exon 6 (an RNA-binding motif), suggests that disruption of extra-ribosomal functions of RPL13 through mRNA binding—rather than ribosomal assembly defects—may underlie the skeletal phenotype, since these variants do not cause significant pre-rRNA processing disturbance. Structural analysis of variant positions, splicing assays, clinical and radiological characterization, mutational clustering analysis NPJ genomic medicine Low 37993442
2024 Bombyx mori RPL13 (BmRPL13) is recruited to sites of UV-induced DNA damage and contributes to UV damage repair. Knockdown of BmRPL13 in BmN cells slows repair of UV-damaged DNA. BmRPL13 interacts with BmNPV ORF65 (Bm65) protein and co-localizes to UV-induced DNA damage sites of BmNPV, facilitating repair of UV-damaged viral DNA. Fluorescence imaging of DNA damage recruitment, siRNA knockdown, UV damage repair assays, co-immunoprecipitation with Bm65 Insect molecular biology Low 38801334

Source papers

Stage 0 corpus · 69 papers · ranked by NIH iCite citations
Year Title Journal Citations PMID
2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 1718 22658674
2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America 1479 12477932
2006 A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 1362 16751776
2015 The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell 1118 26186194
2017 Architecture of the human interactome defines protein communities and disease networks. Nature 1085 28514442
2015 A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell 1015 26496610
2014 A proteome-scale map of the human interactome network. Cell 977 25416956
2005 Nucleolar proteome dynamics. Nature 934 15635413
2004 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nature cell biology 841 14743216
2018 VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell discovery 829 29507755
2002 Directed proteomic analysis of the human nucleolus. Current biology : CB 780 11790298
2003 Complete sequencing and characterization of 21,243 full-length human cDNAs. Nature genetics 754 14702039
2021 Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Cell 705 33961781
2012 A census of human soluble protein complexes. Cell 689 22939629
2015 Gene essentiality and synthetic lethality in haploid human cells. Science (New York, N.Y.) 657 26472760
2011 Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Briefings in bioinformatics 656 21873635
2017 Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science (New York, N.Y.) 533 28302793
2013 Structures of the human and Drosophila 80S ribosome. Nature 481 23636399
2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome research 438 15489334
2022 OpenCell: Endogenous tagging for the cartography of human cellular organization. Science (New York, N.Y.) 432 35271311
2010 Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. Journal of proteome research 422 20020773
2013 The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. The Journal of biological chemistry 413 23463506
2015 Panorama of ancient metazoan macromolecular complexes. Nature 407 26344197
2004 The molecular mechanics of eukaryotic translation. Annual review of biochemistry 396 15189156
2015 Structure of the human 80S ribosome. Nature 380 25901680
2015 Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry. Nature methods 370 26414014
2007 Identification of Protor as a novel Rictor-binding component of mTOR complex-2. The Biochemical journal 357 17461779
2021 A proximity-dependent biotinylation map of a human cell. Nature 339 34079125
2010 Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell 318 21145461
2003 Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Cell 276 14567916
1978 Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 60 S ribosomal subunit proteins La, Lb, Lf, P1, P2, L13', L14, L18', L20, and L38. The Journal of biological chemistry 112 621213
1976 Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 60 S ribosomal subunit proteins L4, L5, L7, L9, L11, L12, L13, L21, L22, L23, L26, L27, L30, L33, L35', L37, and L39. The Journal of biological chemistry 70 1002715
2006 Activation of the ribosomal protein L13 gene in human gastrointestinal cancer. International journal of molecular medicine 65 16786168
2013 The rice nuclear gene WLP1 encoding a chloroplast ribosome L13 protein is needed for chloroplast development in rice grown under low temperature conditions. Plant molecular biology 56 24132771
2018 The mitochondrial ribosomal protein L13 is critical for the structural and functional integrity of the mitochondrion in Plasmodium falciparum. The Journal of biological chemistry 51 29626096
2020 Ribosomal Protein L13 Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus in a Helicase DDX3-Dependent Manner. Journal of virology 50 31619563
2004 P6 protein of Cauliflower mosaic virus, a translation reinitiator, interacts with ribosomal protein L13 from Arabidopsis thaliana. The Journal of general virology 39 15557250
2007 Characterization and expression during development and under environmental stress of the genes encoding ribosomal proteins L11 and L13 in Chironomus riparius. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 34 17507274
2021 Ribosomal Protein L13 Participates in Innate Immune Response Induced by Foot-and-Mouth Disease Virus. Frontiers in immunology 31 34093518
2019 RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature. American journal of human genetics 26 31630789
1985 Cloning and nucleotide sequencing of the genes for ribosomal proteins S9 (rpsI) and L13 (rplM) of Escherichia coli. Molecular & general genetics : MGG 24 3884974
2019 Model system identification of novel congenital heart disease gene candidates: focus on RPL13. Human molecular genetics 23 31625562
1989 Chloroplast ribosomal protein L13 is encoded in the nucleus and is considerably larger than its bacterial homologue. Construction, immunoisolation, and nucleotide sequence (including transit peptide) its cDNA clone from an angiosperm. The Journal of biological chemistry 23 2644249
1993 Two related, low-temperature-induced genes from Brassica napus are homologous to the human tumour bbc1 (breast basic conserved) gene. Plant molecular biology 22 8292785
1995 The Drosophila melanogaster homologue of the human BBC1 gene is highly expressed during embryogenesis. Gene 19 7557437
2004 Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation. Proceedings of the National Academy of Sciences of the United States of America 17 15465910
2020 Novel RPL13 Variants and Variable Clinical Expressivity in a Human Ribosomopathy With Spondyloepimetaphyseal Dysplasia. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 16 32916022
1997 Exclusion of BBC1 and CMAR as candidate breast tumour-suppressor genes. British journal of cancer 16 9413939
1980 Purification of Drosophila ribosomal proteins. Isolation of proteins S8, S13, S14, S16, S19, S20/L24, S22/L26, S24, S25/S27, S26, S29, L4, L10/L11, L12, L13, L16, L18, L19, L27, 1, 7/8, 9, and 11. Biochemistry 16 6773542
2019 Draft genome sequence of a multidrug-resistant blaOXA-69-producing Acinetobacter baumannii L13 isolated from Tarim River sample in China. Journal of global antimicrobial resistance 15 31176070
1994 The yeast nuclear gene MRP-L13 codes for a protein of the large subunit of the mitochondrial ribosome. Current genetics 15 7954901
2001 Enhanced tolerance against salt-stress and freezing-stress of Escherichia coli cells expressing algal bbc1 gene. Current microbiology 13 11270650
1995 Mapping of the breast basic conserved gene (D16S444E) to human chromosome band 16q24.3. Cytogenetics and cell genetics 13 7956357
2019 The S. pombe adaptor protein Bbc1 regulates localization of Wsp1 and Vrp1 during endocytic actin patch assembly. Journal of cell science 12 31391237
1994 The primary structure of rat ribosomal protein L13. Biochemical and biophysical research communications 11 8198561
2017 Complete genome sequence of Pseudomonas brassicacearum strain L13-6-12, a biological control agent from the rhizosphere of potato. Standards in genomic sciences 10 28078051
2004 Molecular characterization of a light-responsive gene, breast basic conserved protein 1 (OsiBBC1), encoding nuclear-localized protein homologous to ribosomal protein L13 from Oryza sativa indica. Biochimica et biophysica acta 10 14746913
1993 Involvement of calcium-dependent cysteine protease in fibronectin-induced chemotactic migration of NIH-L13 fibroblasts. Biochemistry and molecular biology international 7 8364405
1991 Chloroplast ribosomal protein L15, like L1, L13 and L21, is significantly larger than its E. coli homologue. FEBS letters 6 2037044
2023 Clinical, genetic and structural delineation of RPL13-related spondyloepimetaphyseal dysplasia suggest extra-ribosomal functions of eL13. NPJ genomic medicine 4 37993442
1998 Characterization of a Schistosoma mansoni homologue of the gene encoding the breast basic conserved protein 1/L13 ribosomal protein. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 4 9854818
1982 The gene for ribosomal protein L13, rplM, is located near argR, at about 70 minutes on the Escherichia coli chromosomal linkage map. Journal of bacteriology 4 7035437
2023 Evolution of clinical and radiological presentations of spondyloepimetaphyseal dysplasia, RPL13-related: Description of 11 further cases. Clinical genetics 3 37121912
2002 The production of anti-hexapeptide antibodies which recognize the S7, L6 and L13 ribosomal proteins of Escherichia coli. Journal of peptide science : an official publication of the European Peptide Society 3 11931584
2024 Bombyx mori RPL13 participates in UV-induced DNA damage repair of B. mori nucleopolyhedrovirus through interaction with Bm65. Insect molecular biology 2 38801334
2025 Beyond the Known: Expanding the Clinical and Genetic Spectrum of Rare RPL13-Related Spondyloepimetaphyseal Dysplasia. International journal of molecular sciences 1 40725227
2025 Adaptive responses of Rhodococcus aetherivorans L13 to oligotrophy: genome and transcriptomic analysis. Current genetics 0 40220062
2024 [Clinical and genetic analysis of a patient with short stature due to variant of RPL13 gene]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 0 38684306
2023 [Syndromic growth retardation caused by impaired function of the ribosomal protein eL13]. Problemy endokrinologii 0 39069777