Affinage

MYOG

Myogenin · UniProt P15173

Length
224 aa
Mass
25.0 kDa
Annotated
2026-06-10
44 papers in source corpus 17 papers cited in narrative 17 extracted findings
Cross-family judge vs UniProt: Affinage preferred faithfulness: 7/7 claims corpus-supported (100%)

Mechanistic narrative

Synthesis pass · prose summary of the discoveries below

MYOG (myogenin/MYF4) is a nuclear basic helix-loop-helix transcription factor that operates downstream of the upstream myogenic regulatory factors to drive terminal skeletal muscle differentiation (PMID:24385300, PMID:19193870). It functions cooperatively with MYOD rather than independently: MYOD binds late-expressed muscle genes first and recruits histone acetyltransferases to initiate regional histone modification, after which MYOG enhances and fully activates expression of this MYOD-initiated subset of genes (PMID:16437161). Epistasis in zebrafish confirms that MYOG is not sufficient to activate myogenesis de novo without MYOD/Myf5 (PMID:19193870). Acting through E-box elements, MYOG directly transactivates downstream differentiation and fusion genes including Myomaker (PMID:26540045) and Myoz2 (PMID:36191510), and drives additional targets such as SIX1 via a MEF3 motif (PMID:28974698) and LATS2 in concert with MEF2A (PMID:36126508). MYOG expression is itself a tightly controlled node: it is activated by upstream MRFs and a Ski–Six1–Eya3 complex acting at a MEF3 site (PMID:1659574, PMID:19008232), and is repressed by oncogenic RAS–MEK–ERK signaling, which drives ERK2-dependent promoter-proximal RNA polymerase II stalling at the MYOG locus, as well as by the transcriptional repressor TRPS1 (PMID:29973406, PMID:37452493). At the protein level, MYOG activity is constrained by Arp5, which competes with the Pbx1–Meis1 heterodimer for binding to MYOG's cysteine-rich region to disturb MYOD-mediated chromatin remodeling, a mechanism dysregulated in rhabdomyosarcoma (PMID:35348112). No causative coding mutations in MYOG were found in severe congenital myopathy (PMID:10329008).

Mechanistic history

Synthesis pass · year-by-year structured walk · 15 steps
  1. 1991 Medium

    Established that the MYOG promoter is a convergence point for myogenic and signaling inputs, defining how the differentiation program is gated upstream of MYOG itself.

    Evidence Reporter assays with 5' deletions plus forced MRF expression and pharmacological perturbation in 10T1/2 fibroblasts

    PMID:1659574

    Open questions at the time
    • Direct factor occupancy at the promoter not demonstrated
    • Identity of the Gi-protein-coupled effectors unresolved
    • Mostly heterologous fibroblast context
  2. 1999 Low

    Tested whether MYOG coding mutations cause severe congenital myopathy, addressing a possible disease role; the negative result argued against MYOG coding variants as a common cause.

    Evidence PCR sequencing of all three MYOG exons in 37 patients and 40 controls

    PMID:10329008

    Open questions at the time
    • Negative result does not exclude regulatory/intronic variants
    • Limited cohort size
    • No functional follow-up
  3. 2006 High

    Resolved how MYOG and MYOD divide labor at shared targets, showing MYOG acts as an amplifier of a MYOD-initiated chromatin program rather than an independent pioneer factor.

    Evidence Genome-wide ChIP with promoter-specific binding, expression, and histone modification profiling in myoblasts/myotubes

    PMID:16437161

    Open questions at the time
    • Precise coactivators recruited by MYOG not defined
    • Does not specify how MYOG binding is licensed by prior MYOD occupancy
  4. 2008 High

    Identified an upstream activating complex driving MYOG transcription, showing Ski activates MYOG through a MEF3/Six1 element via direct Ski-Six1-Eya3 interaction.

    Evidence Conditional OE/KD of Ski in C2C12, ChIP at the MYOG locus, reporter assays, and Co-IP of the Ski-Six1-Eya3 complex

    PMID:19008232

    Open questions at the time
    • How Ski integrates with MRF inputs at the promoter unclear
    • In vivo requirement during development not addressed
  5. 2009 Medium

    Placed MYOG genetically downstream of MYOD/Myf5 by showing it cannot rescue myogenesis de novo, clarifying its non-redundant late position in the hierarchy.

    Evidence Morpholino knockdown of myod/myf5 in zebrafish with mrf4 vs myog rescue and in vivo imaging

    PMID:19193870

    Open questions at the time
    • Morpholino specificity caveats
    • Does not define which targets require MYOG specifically
  6. 2011 Medium

    Identified PTPLa as a specific upstream activator of MYOG induction, separating MYOG control from MYOD levels during differentiation.

    Evidence siRNA knockdown of PTPLa in myoblasts with MYOG expression readouts and differentiation assays

    PMID:22106411

    Open questions at the time
    • Molecular mechanism linking PTPLa to MYOG promoter unknown
    • Whether effect is direct not established
  7. 2014 Medium

    Confirmed MYOG as a nuclear, non-secretory bHLH factor with intrinsic myogenic trans-differentiation activity capable of inducing muscle markers in non-muscle cells.

    Evidence EGFP-tagged localization microscopy and forced expression inducing desmin in goat embryonic fibroblasts

    PMID:24385300

    Open questions at the time
    • Single ortholog/cell context
    • Does not map nuclear import signals
  8. 2015 Medium

    Connected MYOG to the fusion machinery, showing MYOD and MYOG co-activate Myomaker via a conserved E-box to promote myoblast fusion.

    Evidence Luciferase reporter with E-box mutants and ChIP for MYOD/MYOG at the Myomaker promoter in chicken myoblasts

    PMID:26540045

    Open questions at the time
    • Relative contributions of MYOD vs MYOG not separated
    • Single avian model
  9. 2017 Medium

    Extended the MYOG regulon to SIX1, revealing a feed-forward loop in which MYOG drives SIX1 through a MEF3 motif.

    Evidence EMSA, ChIP, reporter deletion/mutation, and siRNA in bovine cells

    PMID:28974698

    Open questions at the time
    • Indirect mechanism at MEF3 not fully resolved
    • Single lab/species
  10. 2018 High

    Defined a clinically actionable repression mechanism, showing oncogenic RAS-MEK-ERK silences MYOG via ERK2-driven Pol II stalling that is reversible by MEK inhibition.

    Evidence ChIP for ERK2/Pol II at the MYOG promoter, trametinib treatment, RNA-seq, ATAC-seq, and xenografts

    PMID:29973406

    Open questions at the time
    • How ERK2 is recruited to the promoter not fully defined
    • Generality across muscle contexts beyond the tumor models
  11. 2018 Medium

    Identified DEC1 as an additional repressor acting at the MYOG promoter to block differentiation.

    Evidence Adenoviral DEC1 overexpression with MYOG promoter luciferase assay in bovine satellite cells

    PMID:29350420

    Open questions at the time
    • Direct DEC1 promoter occupancy not shown
    • Endogenous loss-of-function not tested
  12. 2022 High

    Uncovered post-translational restraint of MYOG, showing Arp5 competes with Pbx1-Meis1 at the cysteine-rich region to block MYOD-mediated chromatin remodeling, with relevance to rhabdomyosarcoma.

    Evidence Reciprocal Co-IP, competition assays, OE/siRNA, chromatin remodeling and myotube assays, and in vivo mouse limb overexpression

    PMID:35348112

    Open questions at the time
    • Structural basis of CR-region competition not solved
    • How Arp5 levels are set in normal myogenesis unclear
  13. 2022 Medium

    Expanded the direct MYOG target set to Myoz2 and LATS2, reinforcing MYOG's cooperative regulation with MYOD and MEF2A at downstream muscle genes.

    Evidence ChIP, dual-luciferase with deletion/mutation, and siRNA for Myoz2 and LATS2 in bovine cells

    PMID:36126508 PMID:36191510

    Open questions at the time
    • Physiological consequence of LATS2/Myoz2 regulation not tested in vivo
    • Single species
  14. 2022 Low

    Added candidate activating inputs to MYOG, with CREB1 binding the proximal promoter and CSRP3 interacting with MYOG to mediate vitamin-C-driven myogenesis.

    Evidence Dual-luciferase reporter (CREB1) and Co-IP/nuclear fractionation with C2C12 and injury models (CSRP3)

    PMID:35652451 PMID:35777504

    Open questions at the time
    • CREB1 ChIP confirmation not stated
    • CSRP3-MYOG Co-IP not deeply characterized
    • Functional consequences of the interactions incompletely defined
  15. 2023 High

    Established TRPS1 as a direct repressor of MYOG that shares MYOD1 binding sites at the promoter and impairs differentiation in embryonal rhabdomyosarcoma.

    Evidence ChIP for TRPS1/MYOD1 at the MYOG promoter, reporter assays, OE/KD in myoblasts and RD cells, and xenografts

    PMID:37452493

    Open questions at the time
    • How TRPS1 competes with or displaces MYOD at shared sites not resolved
    • Upstream control of TRPS1 beyond miR-1 incompletely mapped

Open questions

Synthesis pass · forward-looking unresolved questions
  • How the multiple repressive (RAS-ERK, TRPS1, DEC1, Arp5) and activating (MRFs, Ski-Six1-Eya3, CREB1, PTPLa) inputs are integrated quantitatively at the MYOG locus to time terminal differentiation, and the structural basis of MYOG cofactor competition, remain unresolved.
  • No unified model coordinating activators and repressors
  • No structural model of MYOG with Arp5/Pbx1-Meis1 or with MYOD
  • MYOG-specific in vivo target requirements incompletely defined

Mechanism profile

Synthesis pass · controlled-vocabulary classification · explore literature graph →
Molecular activity
GO:0140110 transcription regulator activity 6 GO:0003677 DNA binding 3
Localization
GO:0005634 nucleus 1
Pathway
R-HSA-1266738 Developmental Biology 3 R-HSA-74160 Gene expression (Transcription) 3
Partners
ARP5CSRP3MEF2AMYOD1TRPS1

Evidence

Reading pass · 17 per-paper findings extracted from the source corpus
Year Finding Method Journal Conf PMIDs
2006 MYOG and MYOD have distinct regulatory roles at a common set of target genes in skeletal muscle. MYOD binds first and recruits histone acetyltransferases to initiate regional histone modification at late-expressed genes, but is not sufficient for their full expression. MYOG does not bind these late genes efficiently without prior MYOD binding; transcriptional activation of late genes requires the combined activity of MYOD and MYOG. Thus MYOG's role in terminal differentiation is to enhance expression of a subset of genes previously initiated by MYOD. Genome-wide ChIP, promoter-specific DNA binding assays, expression analysis, histone modification profiling in myoblasts/myotubes The EMBO journal High 16437161
2018 Oncogenic RAS, acting through the RAF-MEK-ERK MAPK pathway, represses MYOG expression by causing ERK2-dependent promoter-proximal stalling of RNA polymerase II at the MYOG locus. MEK inhibition with trametinib removes ERK2 from the MYOG promoter, releases transcriptional stalling, and restores MYOG expression. Restored MYOG subsequently opens chromatin and establishes super-enhancers at genes required for late myogenic differentiation. ChIP for ERK2 and Pol II at MYOG promoter, small-molecule inhibitor treatment (trametinib), RNA-seq, ATAC-seq, xenograft tumor models Science translational medicine High 29973406
1991 The MYOG (Myf4) promoter is regulated by multiple signaling pathways: (1) MyoD1, Myf5, and Myf6 transactivate the Myf4 promoter in fibroblasts; (2) serum components, bFGF, TGF-β, and EGF down-regulate Myf4 gene activity; (3) cAMP-elevating agents (dibutyryl-cAMP, forskolin, cholera toxin) inhibit the Myf4 promoter; (4) pertussis toxin (which inactivates Gi protein) stimulates Myf4 expression, indicating positive control through a Gi protein-dependent pathway. A minimal ~200 bp upstream region is sufficient for cell-type-specific expression. CAT/LacZ reporter assays with 5' deletion constructs, forced expression of MRFs in 10T1/2 fibroblasts, pharmacological perturbation with pertussis toxin, cholera toxin, forskolin, dibutyryl-cAMP The Journal of cell biology Medium 1659574
2008 The proto-oncogene Ski is required for muscle terminal differentiation and directly activates transcription of MYOG. Ski occupies the endogenous MYOG regulatory region and activates its transcription primarily through a MEF3 site bound by Six1, not through MyoD or MEF2 binding sites. This requires direct physical interaction of Ski with Six1 and Eya3, mediated by the Dachshund homology domain of Ski. Conditional retroviral overexpression and knockdown of Ski in C2C12 myoblasts, ChIP at the MYOG locus, transcriptional reporter assays, co-immunoprecipitation of Ski-Six1-Eya3 complex The Journal of biological chemistry High 19008232
2015 MYOD and MYOG bind to a conserved E-box element proximal to the Myomaker transcription start site and induce Myomaker transcription, thereby promoting myoblast fusion. Luciferase reporter assays with E-box mutants, ChIP for MYOD and MYOG at the Myomaker promoter in chicken primary myoblasts International journal of molecular sciences Medium 26540045
2022 Actin-related protein 5 (Arp5) acts as an inhibitory regulator of MYOG (and MYOD) by binding to their cysteine-rich (CR) region, which overlaps with the region essential for their epigenetic/chromatin-remodeling functions. Arp5 competes with the Pbx1-Meis1 homeodomain heterodimer for binding to the CR region of MYOG, thereby disturbing MyoD-mediated chromatin remodeling. This inhibitory function is independent of the INO80 chromatin remodeling complex. In rhabdomyosarcoma, elevated Arp5 expression contributes to dysregulation of MYOG activity. Co-immunoprecipitation, overexpression and siRNA knockdown of Arp5 in myoblasts and RMS cells, chromatin remodeling assays, myotube formation assays, in vivo overexpression in mouse hind limbs eLife High 35348112
2011 PTPLa (protein tyrosine phosphatase-like A) is required for myoblast differentiation; cells lacking PTPLa fail to differentiate into myotubes due to repressed MYOG expression. PTPLa loss does not affect MyoD levels but specifically impairs MYOG induction, placing PTPLa upstream of MYOG in the myogenic differentiation pathway. siRNA knockdown of PTPLa in myoblasts, Western blot and qPCR for MYOG expression, differentiation assays Molecular and cellular biology Medium 22106411
2023 The transcriptional repressor TRPS1 directly restricts MYOG expression and thereby inhibits terminal myogenic differentiation. TRPS1 and MYOD1 share common genomic binding sites including the MYOG promoter; TRPS1 occupancy at the MYOG promoter represses MYOG transcription. In embryonal rhabdomyosarcoma, elevated TRPS1 (sustained by miR-1 suppression) impairs myogenic differentiation through this mechanism. ChIP for TRPS1 and MYOD1 at the MYOG promoter, luciferase reporter assays, TRPS1 overexpression and knockdown in myoblasts and RD cells, in vivo xenograft experiments Molecular therapy : the journal of the American Society of Gene Therapy High 37452493
2018 DEC1 (Bhlhe40/STRA13) overexpression inhibits myogenic differentiation in bovine satellite cells by inhibiting MYOG promoter activity, as demonstrated by luciferase reporter assays. DEC1 overexpression reduces MYOG mRNA and protein levels. Adenovirus-mediated DEC1 overexpression, luciferase reporter assay of MYOG promoter, Western blot and qPCR for MYOG in bovine satellite cells Journal of cellular physiology Medium 29350420
2022 CREB1 directly binds to the proximal promoter region of MYOG and activates its transcription, promoting myogenic differentiation in bovine myoblasts, as shown by dual-luciferase reporter assays. Dual-luciferase reporter assay with MYOG promoter constructs, CREB1 overexpression/knockdown, ChIP (inferred from promoter analysis) International journal of biological macromolecules Low 35777504
2017 MYOG drives transcription of the bovine SIX1 gene indirectly via the MEF3 motif in the SIX1 promoter, as shown by EMSA, ChIP, serial deletion constructs, site-directed mutation, and siRNA interference experiments. EMSA, ChIP, luciferase reporter with deletion constructs and site-directed mutations, siRNA knockdown Scientific reports Medium 28974698
2022 MYOG binds to E-box elements in the core promoter region (-159/+1) of the bovine Myoz2 gene and cooperates with MYOD to regulate its transcription, as demonstrated by ChIP, dual-luciferase assay, site-directed mutagenesis, and siRNA interference. ChIP, dual-luciferase reporter with deletion constructs and site-directed mutagenesis, siRNA interference Research in veterinary science Medium 36191510
2022 MEF2A and MYOG cooperate to bind the core promoter region (-248/-56) of the bovine LATS2 gene and regulate its transcription, as identified by site-directed mutations, siRNA interference, and chromatin immunoprecipitation. Dual-luciferase reporter with deletion/mutation constructs, siRNA interference, ChIP Research in veterinary science Medium 36126508
2022 Vitamin C (VC) promotes muscle differentiation by upregulating nuclear translocation of CSRP3, which then interacts physically with MYOG (and MYOD), linking CSRP3-MYOG interaction to VC-mediated myogenesis. Co-immunoprecipitation/interaction assay, nuclear fractionation, C2C12 differentiation assays, mouse muscle injury model Journal of agricultural and food chemistry Low 35652451
2014 Sheep MyoG protein localizes to the nucleus when expressed in transfected cells, and forced expression of MyoG in goat embryonic fibroblasts induces desmin expression, demonstrating its myogenic trans-differentiation activity. MyoG contains a bHLH domain and lacks a signal peptide, identifying it as a non-secretory nuclear transcription factor. EGFP-tagged MyoG transfection with subcellular localization by fluorescence microscopy, Western blot, RT-PCR; forced expression in GEF cells with desmin immunodetection Molecular biology reports Medium 24385300
2009 In zebrafish, myog (unlike mrf4) cannot rescue myogenesis in myod/myf5 double morphants, demonstrating that myog is not sufficient to activate myogenesis de novo in the absence of upstream MRFs. This places myog downstream of myod/myf5 in the zebrafish myogenic hierarchy. Morpholino knockdown of myod and myf5 in zebrafish, rescue experiments with forced early expression of mrf4 or myog, in vivo imaging of muscle development Journal of cell science Medium 19193870
1999 No causative mutations were detected in the MYOG (myf4) coding region in 37 patients with severe congenital myopathy, indicating that coding mutations in MYOG are not a common cause of severe congenital myopathy. Additional intronic sequences (659 bp in intron 1, 498 bp in intron 2) and a variable (CA)-dinucleotide repeat in intron 2 were characterized. PCR amplification and automated sequencing of all three MYOG exons in 37 patients and 40 controls Genomics Low 10329008

Source papers

Stage 0 corpus · 44 papers · ranked by NIH iCite citations
Year Title Journal Citations PMID
2006 Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. The EMBO journal 217 16437161
2018 MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma. Science translational medicine 119 29973406
2015 Myomaker, Regulated by MYOD, MYOG and miR-140-3p, Promotes Chicken Myoblast Fusion. International journal of molecular sciences 96 26540045
1991 Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins. The Journal of cell biology 82 1659574
2020 CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG. Nature communications 44 32060262
2006 Polymorphisms in coding and regulatory regions of the porcine MYF6 and MYOG genes and expression of the MYF6 gene in m. longissimus dorsi versus productive traits in pigs. Journal of applied genetics 39 16682754
2008 Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3. The Journal of biological chemistry 36 19008232
2018 A new hypoglycemic mechanism of catalpol revealed by enhancing MyoD/MyoG-mediated myogenesis. Life sciences 33 30118770
2009 Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo. Journal of cell science 29 19193870
2011 Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway. Molecular and cellular biology 26 22106411
2015 Identification of miR-2400 gene as a novel regulator in skeletal muscle satellite cells proliferation by targeting MYOG gene. Biochemical and biophysical research communications 22 26047700
2017 MiR-2425-5p targets RAD9A and MYOG to regulate the proliferation and differentiation of bovine skeletal muscle-derived satellite cells. Scientific reports 20 28341832
2022 CREB1 promotes proliferation and differentiation by mediating the transcription of CCNA2 and MYOG in bovine myoblasts. International journal of biological macromolecules 19 35777504
2022 MyoG-enhanced circGPD2 regulates chicken skeletal muscle development by targeting miR-203a. International journal of biological macromolecules 19 36208808
2017 Characterization of the promoter region of the bovine SIX1 gene: Roles of MyoD, PAX7, CREB and MyoG. Scientific reports 18 28974698
2022 Vitamin C Promotes Muscle Development Mediated by the Interaction of CSRP3 with MyoD and MyoG. Journal of agricultural and food chemistry 17 35652451
2022 Interaction of MyoD and MyoG with Myoz2 gene in bovine myoblast differentiation. Research in veterinary science 17 36191510
2016 Inhibition of skeletal muscle atrophy during torpor in ground squirrels occurs through downregulation of MyoG and inactivation of Foxo4. Cryobiology 16 27593478
2018 Over-expression of DEC1 inhibits myogenic differentiation by modulating MyoG activity in bovine satellite cell. Journal of cellular physiology 12 29350420
2023 LncRNA TCONS_00323213 Promotes Myogenic Differentiation by Interacting with PKNOX2 to Upregulate MyoG in Porcine Satellite Cells. International journal of molecular sciences 10 37047747
2023 Foxo3 Knockdown Mediates Decline of Myod1 and Myog Reducing Myoblast Conversion to Myotubes. Cells 10 37681900
2022 Actin-related protein 5 functions as a novel modulator of MyoD and MyoG in skeletal muscle and in rhabdomyosarcoma. eLife 10 35348112
2015 Analysis of muscle fibre input dynamics using a myog:GFP transgenic trout model. The Journal of experimental biology 10 25657208
2023 A dysfunctional miR-1-TRPS1-MYOG axis drives ERMS by suppressing terminal myogenic differentiation. Molecular therapy : the journal of the American Society of Gene Therapy 9 37452493
2006 Myogenin (Myf4) upregulation in trans-differentiating fibroblasts from a congenital myopathy with arrest of myogenesis and defects of myotube formation. Anatomy and embryology 9 16977479
2016 Myf5 and MyoG gene SNPs associated with Bian chicken growth trait. Genetics and molecular research : GMR 8 27525903
2021 Lnc-GD2H Promotes Proliferation by Forming a Feedback Loop With c-Myc and Enhances Differentiation Through Interacting With NACA to Upregulate Myog in C2C12 Myoblasts. Frontiers in cell and developmental biology 7 34490239
2008 The effect of interaction between genotype CAST/RsaI (calpastatin) and MYOG/MspI (myogenin) on carcass and meat quality in pigs free of RYR1(T) allele. Meat science 7 22063844
1999 Human bHLH transcription factor gene myogenin (MYOG): genomic sequence and negative mutation analysis in patients with severe congenital myopathies. Genomics 7 10329008
2023 Natural antisense transcript of MYOG regulates development and regeneration in skeletal muscle by shielding the binding sites of MicroRNAs of MYOG mRNA 3'UTR. Biochemical and biophysical research communications 6 37104884
2016 Hepatitis B virus surface protein-induced hPIAS1 transcription requires TAL1, E47, MYOG, NFI, and MAPK signal pathways. Biological chemistry 6 27276529
2014 Cloning and expression of MyoG gene from Hu sheep and identification of its myogenic specificity. Molecular biology reports 6 24385300
2006 Effects of the MyoG gene on the partial growth traits in pigs. Yi chuan xue bao = Acta genetica Sinica 6 17112970
2006 Effect of MYOG genotypes on growth rate and production traits in Hungarian large white pigs. Acta veterinaria Hungarica 5 17020142
2016 Sex- and age-dependent expression of Pax7, Myf 5, MyoG, and Myostatin in yak skeletal muscles. Genetics and molecular research : GMR 4 27420962
2010 The phylogeny analysis of MyoG gene in different pig breeds. Interdisciplinary sciences, computational life sciences 4 20640787
2024 Dietary inclusion of Withania somnifera and Asparagus racemosus induces growth, activities of digestive enzymes, and transcriptional modulation of MyoD, MyoG, Myf5, and MRF4 genes in fish, Channa punctatus. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 3 38237655
2022 Roles of MEF2A and MyoG in the transcriptional regulation of bovine LATS2 gene. Research in veterinary science 3 36126508
2015 Differentiated evolutionary relationships among chordates from comparative alignments of multiple sequences of MyoD and MyoG myogenic regulatory factors. Genetics and molecular research : GMR 1 26505406
2005 [Influences of MyoG gene on reproductive traits in Jinhua pig]. Yi chuan = Hereditas 1 16378935
2026 Global MyoG research 2004-2024: a bibliometric analysis of trends and translational implications. Experimental biology and medicine (Maywood, N.J.) 0 41868599
2025 Single Nucleotide Polymorphisms in the Promoter Region of MyoG Gene Affecting Growth Traits and Transcription Factor Binding Sites in Guizhou White Goat (Capra hircus). Genes 0 41595434
2005 [The genetic effects of MyoG gene]. Yi chuan = Hereditas 0 16257896
1993 Myf-4 does not mediate AChR receptor subunit mRNA expression in thymic tissues. Annals of the New York Academy of Sciences 0 8357157

Missed literature

Know a paper Affinage missed for MYOG? Flag it for the maintainers and the community.

No submissions yet.