CLTB
Clathrin light chain B · UniProt P09497
- Length
- 229 aa
- Mass
- 25.2 kDa
- Annotated
- 2026-04-28
46 papers in source corpus
Mechanistic narrative
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Mechanism profile
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Source papers
Stage 0 corpus · 46 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2005 | A human protein-protein interaction network: a resource for annotating the proteome. | Cell | 1704 | 16169070 |
| 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Proceedings of the National Academy of Sciences of the United States of America | 1479 | 12477932 |
| 2015 | A human interactome in three quantitative dimensions organized by stoichiometries and abundances. | Cell | 1015 | 26496610 |
| 2021 | Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. | Cell | 705 | 33961781 |
| 2011 | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Briefings in bioinformatics | 656 | 21873635 |
| 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | Genome research | 438 | 15489334 |
| 2022 | OpenCell: Endogenous tagging for the cartography of human cellular organization. | Science (New York, N.Y.) | 432 | 35271311 |
| 2015 | Panorama of ancient metazoan macromolecular complexes. | Nature | 407 | 26344197 |
| 2007 | Functional specialization of beta-arrestin interactions revealed by proteomic analysis. | Proceedings of the National Academy of Sciences of the United States of America | 360 | 17620599 |
| 2021 | A proximity-dependent biotinylation map of a human cell. | Nature | 339 | 34079125 |
| 2012 | Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. | PloS one | 312 | 23251661 |
| 2004 | Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. | Nature biotechnology | 266 | 15146197 |
| 2017 | Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification. | Nature communications | 221 | 28524877 |
| 2016 | An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. | Nature communications | 211 | 27173435 |
| 2009 | Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. | Science signaling | 207 | 19738201 |
| 2018 | An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations. | Nature communications | 201 | 29568061 |
| 2015 | CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature. | Developmental cell | 164 | 25898166 |
| 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | American journal of human genetics | 164 | 19913121 |
| 2019 | A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape. | Nature immunology | 159 | 30833792 |
| 2011 | A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. | The EMBO journal | 131 | 21297582 |
| 1999 | Clathrin self-assembly is mediated by a tandemly repeated superhelix. | Nature | 125 | 10360576 |
| 2008 | Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. | Journal of neural transmission (Vienna, Austria : 1996) | 117 | 19034380 |
| 2015 | KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II. | Molecular cell | 113 | 26725010 |
| 1986 | Clathrin-coated vesicles contain two protein kinase activities. Phosphorylation of clathrin beta-light chain by casein kinase II. | The Journal of biological chemistry | 109 | 2874131 |
| 2022 | EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation. | Nature communications | 99 | 35013218 |
| 2014 | A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells. | eLife | 98 | 25107275 |
| 2004 | Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo. | The Journal of biological chemistry | 95 | 15533940 |
| 1997 | Nef-mediated clathrin-coated pit formation. | The Journal of cell biology | 95 | 9314527 |
| 2002 | HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain. | The Journal of biological chemistry | 89 | 11889126 |
| 2020 | Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases. | Molecular cell | 88 | 32707033 |
| 1987 | Clathrin light chains LCA and LCB are similar, polymorphic, and share repeated heptad motifs. | Science (New York, N.Y.) | 88 | 3563513 |
| 1990 | Predominance of clathrin light chain LCb correlates with the presence of a regulated secretory pathway. | The Journal of cell biology | 67 | 2211818 |
| 1988 | Identification of the phosphorylation sites of clathrin light chain LCb. | The Journal of biological chemistry | 42 | 3128543 |
| 2016 | Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB Δ8-desaturation and C9-methylation are relevant to filamentous growth, lipid raft localization and Psd1 defensin activity. | Molecular microbiology | 34 | 27479571 |
| 2011 | LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation. | The Journal of pharmacology and experimental therapeutics | 31 | 22128347 |
| 2008 | Degradation of sphingoid long-chain base 1-phosphates (LCB-1Ps): functional characterization and expression of AtDPL1 encoding LCB-1P lyase involved in the dehydration stress response in Arabidopsis. | Plant & cell physiology | 31 | 18849574 |
| 2006 | The LCB Data Warehouse. | Bioinformatics (Oxford, England) | 31 | 16455749 |
| 2013 | Topical administration of the pan-Src kinase inhibitors, dasatinib and LCB 03-0110, prevents allergic contact dermatitis in mice. | The British journal of dermatology | 14 | 23020072 |
| 2014 | Fpk1/2 kinases regulate cellular sphingoid long-chain base abundance and alter cellular resistance to LCB elevation or depletion. | MicrobiologyOpen | 12 | 24510621 |
| 1994 | Chromosomal location and some structural features of human clathrin light-chain genes (CLTA and CLTB). | Genomics | 12 | 7713494 |
| 2022 | Overexpression of a ceramide synthase gene,GhCS1, inhibits fiber cell initiation and elongation by promoting the synthesis of ceramides containing dihydroxy LCB and VLCFA. | Frontiers in plant science | 8 | 36119591 |
| 2024 | Orm proteins control ceramide synthesis and endocytosis via LCB-mediated Ypk1 regulation. | Journal of lipid research | 3 | 39490931 |
| 2017 | In Vitro Activities of LCB 01-0648, a Novel Oxazolidinone, against Gram-Positive Bacteria. | Molecules (Basel, Switzerland) | 3 | 28273820 |
| 1994 | LCB 2183 inhibits the inflammation associated with oxazolone-induced contact sensitivity. | International journal of immunopharmacology | 3 | 7989136 |
| 2024 | Statistical Experimental Designs for cLTB-Syn Vaccine Production Using Daucus carota Cell Suspension Cultures. | Planta medica | 1 | 38698590 |
| 2024 | Anti-inflammatory effects of LCB 03-0110 on human corneal epithelial and murine T helper 17 cells. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology | 1 | 39539175 |