- Length
- 190 aa
- Mass
- 20.7 kDa
- Annotated
- 2026-06-14
36 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 36 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2004 | Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. | British journal of pharmacology | 363 | 14757700 |
| 2010 | Long-term observational, non-randomized study of enzyme replacement therapy in late-onset glycogenosis type II. | Journal of inherited metabolic disease | 75 | 20838899 |
| 1999 | Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator. | The Journal of biological chemistry | 70 | 10318868 |
| 2022 | Disposable Puff Bar Electronic Cigarettes: Chemical Composition and Toxicity of E-liquids and a Synthetic Coolant. | Chemical research in toxicology | 46 | 35849830 |
| 1985 | Western equine encephalomyelitis virus: in vivo infection and morphogenesis in mosquito mesenteronal epithelial cells. | Virus research | 31 | 3993231 |
| 2017 | The long noncoding RNA SPRIGHTLY acts as an intranuclear organizing hub for pre-mRNA molecules. | Science advances | 30 | 28508063 |
| 2019 | Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes. | Aging cell | 27 | 31259468 |
| 2005 | Heterokaryon formation and parasexual recombination between vegetatively incompatible lineages in a population of the chestnut blight fungus, Cryphonectria parasitica. | Molecular ecology | 25 | 16202087 |
| 2013 | Dynamics of withanolide biosynthesis in relation to temporal expression pattern of metabolic genes in Withania somnifera (L.) Dunal: a comparative study in two morpho-chemovariants. | Molecular biology reports | 22 | 24190485 |
| 2025 | Synthetic cooling agent in oral nicotine pouch products marketed as 'Flavour-Ban Approved'. | Tobacco control | 21 | 37380351 |
| 2023 | A Cut-to-Link Strategy for Cubane-Based Heterometallic Sulfide Clusters with Giant Third-Order Nonlinear Optical Response. | Journal of the American Chemical Society | 18 | 37126789 |
| 2017 | Trigeminal Receptor Study of High-Intensity Cooling Agents. | Journal of agricultural and food chemistry | 17 | 28042937 |
| 2019 | Structural Glycoprotein E2 of Classical Swine Fever Virus Interacts with Host Protein Dynactin Subunit 6 (DCTN6) during the Virus Infectious Cycle. | Journal of virology | 12 | 31597779 |
| 2010 | Screening and identification of differentially expressed genes from chickens infected with Newcastle disease virus by suppression subtractive hybridization. | Avian pathology : journal of the W.V.P.A | 10 | 20544419 |
| 2020 | Effect of Physical Form and Level of Wheat Straw Inclusion on Growth Performance and Blood Metabolites of Fattening Goat. | Animals : an open access journal from MDPI | 9 | 33066014 |
| 2022 | Dynactin 2 acts as an oncogene in hepatocellular carcinoma through promoting cell cycle progression. | Liver research (Beijing, China) | 7 | 39958200 |
| 2021 | Dynactin 6 deficiency enhances aging-associated dystrophic neurite formation in mouse brains. | Neurobiology of aging | 7 | 34371284 |
| 2024 | Development, characterization, and evaluation of withaferin-A and artesunate-loaded pH-responsive acetal-dextran polymeric nanoparticles for the management of malaria. | International journal of biological macromolecules | 5 | 38897506 |
| 2023 | Synthetic Cooling Agent in Oral Nicotine Pouch Products Marketed as "Flavor-Ban Approved". | bioRxiv : the preprint server for biology | 5 | 36865160 |
| 1997 | Cloning and characterization of a novel gene, WS-3, in human chromosome 8p11-p12. | Gene | 5 | 9168138 |
| 2025 | Anti-seizure effects of WS-3, a TRPM8 agonist, on focal onset seizure mouse model via reduction of extracellular glutamate levels. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | 4 | 40571799 |
| 2021 | Effects of starter protein content and alkali processing of wheat straw on growth, ruminal fermentation, and behavior in Holstein calves. | Journal of dairy science | 4 | 33455786 |
| 2018 | Effect of cellobiose supplementation and dietary soluble fibre content on in vitro caecal fermentation of carbohydrate-rich substrates in rabbits. | Archives of animal nutrition | 4 | 29701493 |
| 2017 | Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents. | Bioorganic & medicinal chemistry letters | 4 | 28662813 |
| 2023 | Synthetic Cooling Agent and Candy Flavors in California-marketed "non-Menthol" Cigarettes. | bioRxiv : the preprint server for biology | 3 | 37292602 |
| 1991 | Expression of 'small cell carcinoma antigens' in primary small cell lung cancer and metastases: an immunohistochemical study. | The British journal of cancer. Supplement | 3 | 1645571 |
| 2023 | Suppressive effects of a transient receptor potential melastatin 8 (TRPM8) agonist on hyperthermia-induced febrile seizures in infant mice. | Frontiers in pharmacology | 2 | 36969879 |
| 2023 | Modeling and optimization of laying hen manure drying process to reduce protein and ammonium-N losses by adding sodium bentonite and wheat straw. | Journal of environmental management | 2 | 38056333 |
| 2026 | Identification of a Potential Direct-Acting DNA Ethylating Agent Originating from the Synthetic Cooling Agent N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide (WS-3). | Chemical research in toxicology | 0 | 42081608 |
| 2026 | From cool to non-cool: California's 'non-menthol' cigarettes in 2025. | Tobacco prevention & cessation | 0 | 42211562 |
| 2025 | Absence of Sensory Cooling Activity and Cooling Agents from California's New "Non-Menthol" Cigarettes Marketed in 2025. | bioRxiv : the preprint server for biology | 0 | 41332534 |
| 2025 | Pre- and Post-Flavor Ban Oral Nicotine Pouches: A Chemical, Sensory, and Young Adult Appeal Analysis. | medRxiv : the preprint server for health sciences | 0 | 41415510 |
| 2025 | Differences in "minty" flavor compound and synthetic cooling agent presence in US-marketed menthol-mint e-liquids and devices between 2019-2023. | Research square | 0 | 41510256 |
| 2025 | Cooling sensation biosensor coupled with the Chou-Talalay method for quantitative assessment of interaction patterns in binary cooling agent mixtures. | Current research in food science | 0 | 41551171 |
| 2025 | The ketogenic diet alters microbiome-metabolome profiles to improve West syndrome therapy. | Pediatric investigation | 0 | 41726584 |
| 2022 | Carcase characteristics, meat quality, nutrient composition, serum biochemistry and oxidant/antioxidant status in white striping-affected broiler chickens fed diets based on maize-soybean meal. | British poultry science | 0 | 35848771 |
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