ANP32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B · UniProt Q92688
Audit flag: ungrounded claim
- Length
- 251 aa
- Mass
- 28.8 kDa
- Annotated
- 2026-06-14
26 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 26 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2019 | Fundamental Contribution and Host Range Determination of ANP32A and ANP32B in Influenza A Virus Polymerase Activity. | Journal of virology | 70 | 30996088 |
| 2009 | Downregulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. | Carcinogenesis | 50 | 20015864 |
| 2007 | Promoter region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5. | Molecular and cellular biology | 43 | 18039846 |
| 2023 | Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus. | Journal of virology | 39 | 37074204 |
| 2024 | Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation. | Nature communications | 38 | 38750014 |
| 2010 | Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain. | Journal of molecular biology | 34 | 20538007 |
| 2014 | ANP32B is a nuclear target of henipavirus M proteins. | PloS one | 28 | 24823948 |
| 2022 | BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes. | Cancer biology & therapy | 27 | 36170346 |
| 2016 | ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation. | Cell death & disease | 24 | 26844697 |
| 2021 | Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c. | Redox biology | 23 | 33882408 |
| 2019 | The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice. | Scientific reports | 17 | 30890743 |
| 2019 | ANP32A and ANP32B are key factors in the Rev-dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA. | The Journal of biological chemistry | 16 | 31444273 |
| 2017 | Downregulation of ANP32B exerts anti-apoptotic effects in hepatocellular carcinoma. | PloS one | 16 | 28486557 |
| 2020 | Interaction of host cellular factor ANP32B with matrix proteins of different paramyxoviruses. | The Journal of general virology | 14 | 31793855 |
| 1997 | Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family. | Biochemistry and molecular biology international | 14 | 9285060 |
| 2021 | ANP32B-mediated repression of p53 contributes to maintenance of normal and CML stem cells. | Blood | 13 | 34359074 |
| 2012 | Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) contributes to retinoic acid-induced differentiation of leukemic cells. | Biochemical and biophysical research communications | 13 | 22705300 |
| 2021 | A natural variant in ANP32B impairs influenza virus replication in human cells. | The Journal of general virology | 12 | 34524075 |
| 2024 | Super enhancer related gene ANP32B promotes the proliferation of acute myeloid leukemia by enhancing MYC through histone acetylation. | Cancer cell international | 9 | 38383388 |
| 2023 | ANP32B suppresses B-cell acute lymphoblastic leukemia through activation of PU.1 in mice. | Cancer science | 7 | 37137487 |
| 2017 | Prothymosin α interacts with SET, ANP32A and ANP32B and other cytoplasmic and mitochondrial proteins in proliferating cells. | Archives of biochemistry and biophysics | 5 | 29106904 |
| 2023 | ANP32B promotes lung cancer progression by regulating VDAC1. | Gene | 4 | 36642319 |
| 2023 | ANP32B promotes colorectal cancer cell progression and reduces cell sensitivity to PRAP1 inhibitor through up-regulating HPF1. | Heliyon | 3 | 38192816 |
| 2015 | BALB/c-congenic ANP32B-deficient mice reveal a modifying locus that determines viability. | Experimental animals | 3 | 26558540 |
| 2024 | ANP32B inhibition suppresses the growth of prostate cancer cells by regulating c-Myc signaling. | Biochemical and biophysical research communications | 1 | 38266312 |
| 2024 | Anp32b Deficiency Suppresses Ocular Development by Repression of Pax6. | Ophthalmic research | 0 | 39504945 |
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