Showing VCPIP1 — VCIP135 is a alias.
- Length
- 1222 aa
- Mass
- 134.3 kDa
- Annotated
- 2026-06-13
19 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 19 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2002 | VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. | The Journal of cell biology | 181 | 12473691 |
| 2004 | VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. | The Journal of cell biology | 130 | 15037600 |
| 2017 | Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication. | Proceedings of the National Academy of Sciences of the United States of America | 47 | 28584101 |
| 2005 | NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent reformation of the ER network. | Genes to cells : devoted to molecular & cellular mechanisms | 46 | 16164599 |
| 2011 | VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion. | The EMBO journal | 36 | 21811234 |
| 2015 | Cell cycle regulation of VCIP135 deubiquitinase activity and function in p97/p47-mediated Golgi reassembly. | Molecular biology of the cell | 33 | 25904330 |
| 2013 | Phosphorylation regulates VCIP135 function in Golgi membrane fusion during the cell cycle. | Journal of cell science | 24 | 24163436 |
| 2022 | Hepatitis B Virus X Protein Is Stabilized by the Deubiquitinating Enzyme VCPIP1 in a Ubiquitin-Independent Manner by Recruiting the 26S Proteasome Subunit PSMC3. | Journal of virology | 14 | 35695579 |
| 2024 | Molecular Basis of VCPIP1 and P97/VCP Interaction Reveals Its Functions in Post-Mitotic Golgi Reassembly. | Advanced science (Weinheim, Baden-Wurttemberg, Germany) | 7 | 39234822 |
| 2025 | VCPIP1 facilitates pancreatic adenocarcinoma progression via Hippo/YAP signaling. | Cell death & disease | 5 | 40436845 |
| 2023 | VCIP135 associates with both the N- and C-terminal regions of p97 ATPase. | The Journal of biological chemistry | 5 | 38072049 |
| 2024 | VCPIP1 negatively regulates NF-κB signaling pathways by deubiquitinating and stabilizing Erbin in MDP-stimulated macrophages. | International immunopharmacology | 4 | 39550842 |
| 2024 | Identification and characterization of host factor VCPIP1 as a multi-functional positive regulator of hepatitis B virus. | Journal of virology | 3 | 39494904 |
| 2025 | VCPIP1 ameliorates sepsis-associated encephalopathy by promoting microglia autophagy via the PI3K/AKT/mTOR pathway. | International immunopharmacology | 2 | 40865405 |
| 2025 | VCPIP1 potentiates innate immune responses by non-catalytically reducing the ubiquitination of IRAK1/2. | Cell reports | 1 | 40581931 |
| 2025 | Structural basis of VCP-VCPIP1-p47 ternary complex in Golgi maintenance. | Nature communications | 1 | 40877265 |
| 2026 | A GJA1 Variant Triggers Earlier SPG4 Onset by Destabilizing Deubiquitinase VCPIP1 to Lower SPASTIN Levels. | Movement disorders : official journal of the Movement Disorder Society | 0 | 41748310 |
| 2026 | VCPIP1 drives diabetic cardiomyopathy by deubiquitinating AMPKγ1 and preventing AMPKα-γ subunit assembly in cardiomyocytes. | Signal transduction and targeted therapy | 0 | 42144399 |
| 2024 | Analyses of the MYBL1 Gene in Triple Negative Breast Cancer: Evidence of Regulation of the VCPIP1 Gene and Identification of a Specific Exon Overexpressed in Tumor Cell Lines. | International journal of molecular sciences | 0 | 39796135 |
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