Affinage

STAG3

Cohesin subunit SA-3 · UniProt Q9UJ98

Length
1225 aa
Mass
139.0 kDa
Annotated
2026-06-10
42 papers in source corpus 17 papers cited in narrative 16 extracted findings
Cross-family judge vs UniProt: Affinage preferred faithfulness: 7/7 claims corpus-supported (100%)

Mechanistic narrative

Synthesis pass · prose summary of the discoveries below

STAG3 is a meiosis-specific stromal antigen subunit of the cohesin complex that provides the structural scaffold for meiotic chromosome architecture, synapsis, and recombination (PMID:24992337, PMID:24797474). It physically associates with the SMC1/SMC3 core and binds each of the three meiotic α-kleisins (REC8, RAD21L, RAD21) in spermatocytes, and these distinct STAG3-kleisin complexes carry out specialized tasks: STAG3/REC8 cohesin drives centromeric cohesion and chromosome axis formation, while STAG3/RAD21L cohesin supports pericentromeric heterochromatin clustering (PMID:11483963, PMID:27172213). STAG3 is required for the stability and axial loading of all meiosis-specific cohesin subunits without disturbing mitotic cohesin, and its loss abolishes bona fide axial element (SYCP3) assembly, blocks SYCP1-dependent synapsis, impairs centromeric and telomeric sister chromatid cohesion, and permits initiation but not completion of RAD51/DMC1-mediated double-strand break repair, causing prophase I arrest and apoptosis in both sexes (PMID:24992337, PMID:24797474, PMID:24608227). A key non-redundant function is nuclear delivery of its kleisin partner: STAG3 binding through its armadillo-type fold domain is obligately required for REC8 nuclear entry, chromatin loading, and engagement of the cohesin regulators PDS5, WAPL, and sororin, and in-frame deletions in this domain abolish STAG3-REC8/SMC1A interaction and block nuclear import as a cause of human meiotic disease (PMID:29724914, PMID:31803224). Cohesin axis function is gated by CK1-mediated phosphorylation of the STAG3 ortholog Rec11, which promotes its interaction with the axis component Rec10 and linear element assembly independently of cohesion (PMID:25579976, PMID:25993311). In somatic cells STAG3 is transcriptionally silenced by E2F6 acting with PRC2/Ezh2 through H3K9/K27 methylation (PMID:16236716, PMID:23880518). In cancer contexts STAG3 behaves as a context-dependent factor, with loss conferring BRAF-inhibitor resistance in melanoma and METTL3/IGF2BP2-mediated m6A modification stabilizing its mRNA to promote colorectal cancer proliferation (PMID:27500726, PMID:37828232).

Mechanistic history

Synthesis pass · year-by-year structured walk · 12 steps
  1. 2000 Medium

    Established STAG3 as a testis-restricted protein localizing to the synaptonemal complex, framing it as a candidate meiotic cohesin rather than a ubiquitous cohesin subunit.

    Evidence cDNA cloning, expression analysis, and immunolocalization in testis sections

    PMID:10698974

    Open questions at the time
    • No direct binding partners identified
    • Functional requirement not tested by loss-of-function
  2. 2001 High

    Showed STAG3 physically associates with the cohesin core SMC1/SMC3 and localizes to chromosome arms in meiosis I, placing it inside the cohesin complex as a meiosis-specific arm-cohesion subunit.

    Evidence Co-immunoprecipitation and immunofluorescence in meiotic cells

    PMID:11483963

    Open questions at the time
    • Kleisin partner not yet defined
    • Mechanism of arm-specific localization unresolved
  3. 2005 High

    Identified how STAG3 is kept off in somatic tissue, showing E2F6 binds the STAG3 promoter and represses it via H3K9/K27 methylation.

    Evidence Microarray of E2f6-/- MEFs, promoter ChIP, and rescue/histone methylation analysis

    PMID:16236716

    Open questions at the time
    • Enzymatic effector of the methylation not yet defined
    • Developmental timing of silencing not established
  4. 2010 Medium

    Extended the cohesin localization model to human female meiosis, showing STAG3 co-localizes with REC8/SMC1β/SMC3 at lateral elements, arms, and centromeres across meiotic stages.

    Evidence Immunofluorescence of human oocytes at multiple meiotic stages with SYCP3 and shugoshin 1

    PMID:20634189

    Open questions at the time
    • Descriptive localization without functional perturbation in human cells
    • Single lab
  5. 2013 Medium

    Defined the enzymatic basis of somatic silencing, showing E2F6 repression of Stag3 requires the Ezh2 SET domain and is independent of Dnmt3b.

    Evidence Ezh2 SET-domain deletion and Dnmt3b-KO embryoid bodies with ChIP and RT-qPCR

    PMID:23880518

    Open questions at the time
    • Driver of associated promoter DNA methylation unidentified
    • Direct E2F6-PRC2 recruitment mechanism not shown
  6. 2014 High

    Knockout and hypomorphic mouse studies established STAG3 as the master meiotic STAG subunit required for stability and axial loading of all meiotic cohesins, axial element formation, synapsis, cohesion, and DSB repair, with kleisin-specific dosage requirements.

    Evidence Multiple independent Stag3 KO and hypomorphic mouse models with meiotic spread immunofluorescence, western blot, and RAD51/DMC1 foci analysis

    PMID:24608227 PMID:24797474 PMID:24797475 PMID:24992337

    Open questions at the time
    • Molecular basis for differential kleisin dependence not resolved
    • Direct contribution to DSB repair step blocked not mechanistically defined
  7. 2016 High

    Genetic epistasis separated the functions of distinct STAG3-kleisin cohesins, assigning centromeric cohesion/axis formation to STAG3/REC8 and pericentromeric heterochromatin clustering to STAG3/RAD21L, and confirmed direct STAG3 binding to all three α-kleisins.

    Evidence Double-knockout mouse combinations, meiotic spread immunofluorescence, and interaction assays in primary spermatocytes

    PMID:27172213

    Open questions at the time
    • Structural determinants of kleisin selectivity not defined
    • Mechanism coupling RAD21L cohesin to heterochromatin clustering unknown
  8. 2017 Medium

    Revealed a non-canonical STAG3 association with the oocyte spindle, where depletion disrupts spindle assembly, kinetochore-microtubule attachment, and tubulin stability, linking STAG3 to chromosome segregation fidelity.

    Evidence Morpholino knockdown in mouse oocytes with spindle/chromosome immunofluorescence, tubulin acetylation, cold-stable microtubule assay, and FISH aneuploidy scoring

    PMID:27906670

    Open questions at the time
    • Whether spindle effect is cohesin-dependent or a separate role unclear
    • Direct STAG3-microtubule interaction not demonstrated
  9. 2015 High

    Demonstrated regulatory control of cohesin axis function by CK1 phosphorylation of the STAG3 ortholog Rec11, which licenses Rec10 binding and linear element assembly independently of cohesion.

    Evidence In vitro phosphorylation assays, kinase mutants, fission yeast genetics, and a Rec11-Rec10 fusion bypass experiment (two independent studies)

    PMID:25579976 PMID:25993311

    Open questions at the time
    • Mammalian STAG3 phosphosites and the equivalent axis partner not mapped
    • Functional consequence of STAG3 phosphorylation in mammals untested
  10. 2018 High

    Reconstitution in somatic cells showed STAG3 is necessary and sufficient to import its kleisin REC8 into the nucleus and load it onto chromatin, where REC8-STAG3 cohesin engages PDS5, WAPL, and sororin and substitutes for mitotic RAD21.

    Evidence HEK293 reconstitution with Co-IP, nuclear localization/chromatin loading immunofluorescence, and cohesion/dissolution assays

    PMID:29724914

    Open questions at the time
    • Import signal/mechanism for the STAG3-REC8 complex not mapped
    • Reconstitution in somatic cells may not fully recapitulate meiotic regulation
  11. 2019 Medium

    Connected STAG3 to human meiotic disease, showing armadillo-domain in-frame deletions abolish STAG3 binding to REC8 and SMC1A and block nuclear entry of both proteins.

    Evidence Localization and Co-IP of mutant versus wild-type STAG3 with REC8 and SMC1A in a cell model

    PMID:31803224

    Open questions at the time
    • Single study without structural validation
    • Variant effects not tested in patient germ cells
  12. 2023 Medium

    Established post-transcriptional control of STAG3 in cancer, showing METTL3-deposited m6A read by IGF2BP2 stabilizes STAG3 mRNA to drive colorectal cancer proliferation and migration.

    Evidence MeRIP, RIP/pulldown, METTL3/IGF2BP2 knockdown with STAG3 rescue, functional assays, and xenografts

    PMID:37828232

    Open questions at the time
    • Downstream effectors of STAG3 in colorectal cancer not defined
    • Relationship to its meiotic cohesin function unclear

Open questions

Synthesis pass · forward-looking unresolved questions
  • How phosphorylation, m6A regulation, and the somatic versus meiotic and cancer-context roles of STAG3 are mechanistically integrated, and the structural basis of its kleisin selectivity, remain unresolved.
  • No structural model of STAG3-kleisin contacts
  • Mammalian STAG3 phosphoregulation not functionally tested
  • Mechanistic link between cohesin role and oncogenic/tumor-suppressive behavior absent

Mechanism profile

Synthesis pass · controlled-vocabulary classification · explore literature graph →
Molecular activity
GO:0005198 structural molecule activity 3 GO:0060090 molecular adaptor activity 2 GO:0008092 cytoskeletal protein binding 1
Localization
GO:0005694 chromosome 4 GO:0005634 nucleus 2 GO:0005815 microtubule organizing center 1
Pathway
R-HSA-1474165 Reproduction 3 R-HSA-74160 Gene expression (Transcription) 2 R-HSA-1640170 Cell Cycle 1
Partners
PDS5RAD21RAD21LREC8SMC1SMC1ASMC3WAPL
Complex memberships
meiotic cohesin complexsynaptonemal complex (lateral element associated)

Evidence

Reading pass · 16 per-paper findings extracted from the source corpus
Year Finding Method Journal Conf PMIDs
2001 STAG3 physically interacts with SMC1 and SMC3, the structural maintenance of chromosomes proteins that are subunits of the mitotic cohesin complex, establishing STAG3 as a cohesin subunit specific to meiosis I sister chromatid arm cohesion. Co-immunoprecipitation; immunofluorescence localization in meiotic cells Nature cell biology High 11483963
2000 STAG3 is expressed specifically in testis and associates with the synaptonemal complex during pachytene, consistent with a cohesin-like role in chromosome pairing and maintenance of synaptonemal complex structure during meiosis. Immunolocalization in testis sections; cDNA cloning and expression analysis FASEB journal Medium 10698974
2014 STAG3 is required for the stability and chromosomal axis localization of all meiosis-specific cohesin subunits (SMC1β, RAD21L, REC8); in Stag3 knockout mice, these subunits are reduced in protein level and fail to load onto chromosome axes, while the mitotic cohesin complex remains intact. Loss of STAG3 also disrupts DNA repair, homolog synapsis, pericentromeric heterochromatin clustering, and centromere cohesion, causing early prophase I arrest and apoptosis in both sexes. Knockout mouse model; immunofluorescence on meiotic spreads; western blot PLoS genetics High 24992337
2014 STAG3 deficiency in mice (both sexes) causes failure of bona fide axial element formation, absence of SYCP3 axial elements (which form only dot-like structures near centromeres), diffuse HORMAD1 distribution, near-complete absence of SYCP1, and impaired centromeric and telomeric sister chromatid cohesion. Centromere and telomere clustering still occurs in the absence of STAG3. The phenotype is more severe than any other single meiotic cohesin knockout, establishing STAG3 as the key meiotic STAG cohesin. Knockout mouse model; immunofluorescence on meiotic chromosome spreads The EMBO journal High 24797474
2014 STAG3 stabilizes REC8-containing cohesin complexes; in mice with a hypomorphic Stag3 allele (severely reduced STAG3), the three α-kleisins (REC8, RAD21L, RAD21) show different dosage-dependent requirements for STAG3, and STAG3-REC8 cohesin complexes have a critical role in supporting meiotic chromosome structure, axis compaction, synapsis, and recombination. Hypomorphic mouse allele; immunofluorescence; western blot The EMBO journal High 24797475
2014 Male mice devoid of Stag3 exhibit meiotic arrest at a zygonema-like stage with shortening of chromosome axial/lateral elements, partial loss of centromeric cohesion at early prophase, and the ability to initiate but not complete RAD51- and DMC1-mediated double-strand break repair, demonstrating STAG3 as a crucial cohesin subunit in mammalian male gametogenesis. Knockout mouse model; immunofluorescence on meiotic spreads; RAD51/DMC1 foci analysis Human molecular genetics High 24608227
2016 Genetic epistasis analysis using double knockout mice shows that STAG3/REC8 cohesins are the primary cohesin complex required for centromeric cohesion and chromosome axis formation, while STAG3/RAD21L cohesins are required for normal pericentromeric heterochromatin clustering. STAG3 interacts directly with each α-kleisin subunit (REC8, RAD21L, RAD21) in primary spermatocytes. Double knockout mouse models; immunofluorescence on meiotic spreads; genetic epistasis G3 (Bethesda, Md.) High 27172213
2005 E2F6, a retinoblastoma-independent transcriptional repressor, is required to silence STAG3 (and SMC1β) in somatic cells. E2F6 binds in vivo to the STAG3 promoter through a conserved binding site, and this repression involves histone H3 methylation on lysine 9 and lysine 27. cDNA microarray comparing wild-type vs. E2f6-/- MEFs; ChIP at STAG3 promoter; re-expression rescue experiment; histone methylation analysis The Journal of biological chemistry High 16236716
2013 E2F6-mediated repression of Stag3 (and Smc1β) in somatic cells requires the enzymatic (SET domain) activity of Ezh2, a PRC2 complex component, and occurs independently of the de novo methyltransferase Dnmt3b. Repression is established at the transition from ESCs to epiblast stem cells, coinciding with promoter DNA methylation, though Dnmt3b is not the driver. Ezh2 SET domain deletion; Dnmt3b knockout embryoid bodies; ChIP; RT-qPCR Epigenetics Medium 23880518
2015 In fission yeast, casein kinase 1 (CK1) phosphorylates the meiotic cohesin subunit Rec11/SA3 (the fission yeast ortholog of STAG3). This phosphorylation mediates interaction with the chromosome axis component Rec10/Red1/SCP2, thereby promoting linear element (meiotic chromosome axis) assembly and meiotic recombination, independently of sister chromatid cohesion. Expression of Rec11-Rec10 fusion protein bypasses the requirement for CK1 or cohesin phosphorylation for this process. STAG3, the mammalian functional homolog of Rec11, is also phosphorylated during meiosis. In vitro phosphorylation assay; kinase mutants; fission yeast genetics; linear element immunofluorescence; Rec11-Rec10 fusion bypass experiment Developmental cell High 25579976 25993311
2018 When expressed in HEK293 somatic cells, the meiotic kleisin REC8 has no affinity for STAG1 or STAG2 and remains cytoplasmic; however, co-expression of STAG3 is sufficient for REC8 to enter the nucleus, load onto chromatin, and functionally replace its mitotic counterpart RAD21 during sister chromatid cohesion and dissolution. REC8-STAG3 cohesin physically interacts with PDS5, WAPL, and sororin, and is susceptible to WAPL-dependent ring opening and sororin-mediated protection. Somatic cell reconstitution (HEK293); co-immunoprecipitation; immunofluorescence for nuclear localization and chromatin loading; cohesion/dissolution assays Journal of cell science High 29724914
2019 In-frame deletion variants in the STAG3 armadillo-type fold domain (p.293_295del and p.297_298insAsp) are pathogenic: mutant STAG3 and REC8 fail to enter the nucleus, and co-immunoprecipitation shows absence of interaction between mutant STAG3 and REC8 or SMC1A in an in vitro cell model. Fluorescence localization in transfected cells; co-immunoprecipitation of mutant vs. wild-type STAG3 with REC8 and SMC1A Frontiers in genetics Medium 31803224
2017 STAG3 uniquely accumulates on the spindle apparatus and colocalizes with microtubule fibers during mouse oocyte meiotic maturation. Morpholino-mediated depletion of Stag3 disrupts spindle assembly, chromosome alignment, kinetochore-microtubule attachment, reduces acetylated tubulin levels, and decreases microtubule resistance to depolymerizing drugs, resulting in increased aneuploidy in eggs. Morpholino knockdown in mouse oocytes; immunofluorescence for spindle and chromosome markers; tubulin acetylation western blot; cold-stable microtubule assay; FISH for aneuploidy Oncotarget Medium 27906670
2010 In human oocytes, cohesin subunits REC8, STAG3, SMC1β and SMC3 co-localize with the lateral element of the synaptonemal complex at prophase I, are present at centromeres and along chromosomal arms (absent from chiasmata) at metaphase I, and persist at centromeric domains from anaphase I through metaphase II, supporting roles in sister chromatid cohesion throughout human female meiosis. Immunofluorescence on human oocytes at multiple meiotic stages; co-localization with SYCP3 and shugoshin 1 Human reproduction (Oxford, England) Medium 20634189
2016 Loss of STAG3 (or STAG2) expression in BRAF(V600E)-mutant melanoma cells confers resistance to BRAF inhibitors. Knockdown of STAG3 decreased sensitivity of melanoma cells and xenograft tumors to BRAFi, providing evidence for a tumor suppressor role for STAG3 in the context of MAPK signaling. shRNA knockdown in melanoma cell lines; xenograft mouse tumor model; analysis of patient tumor samples with acquired BRAFi resistance Nature medicine Medium 27500726
2023 STAG3 mRNA undergoes N6-methyladenosine (m6A) modification in colorectal cancer cells, mediated by the methyltransferase METTL3 and read by the m6A reader IGF2BP2, which stabilizes STAG3 protein expression. Knockdown of METTL3 decreases both m6A levels and protein expression of STAG3, inhibiting cell proliferation and migration; these effects are rescued by STAG3 overexpression. m6A RNA immunoprecipitation (MeRIP); RIP and pulldown assays for IGF2BP2-STAG3 mRNA interaction; METTL3/IGF2BP2 knockdown and STAG3 overexpression rescue; CCK-8, clone formation, wound healing, flow cytometry; xenograft mouse model Scientific reports Medium 37828232

Source papers

Stage 0 corpus · 42 papers · ranked by NIH iCite citations
Year Title Journal Citations PMID
2001 Mammalian STAG3 is a cohesin specific to sister chromatid arms in meiosis I. Nature cell biology 210 11483963
2000 STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 117 10698974
2014 Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS genetics 107 24992337
2014 Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion. The EMBO journal 89 24797474
2010 Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes. Human reproduction (Oxford, England) 89 20634189
2014 STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. The EMBO journal 85 24797475
2016 Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma. Nature medicine 68 27500726
2019 Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest. Human reproduction (Oxford, England) 65 31682730
2019 Sequencing of a 'mouse azoospermia' gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest. Human reproduction (Oxford, England) 64 31125047
2014 STAG3 is a strong candidate gene for male infertility. Human molecular genetics 62 24608227
1997 Purification of ribonucleases Sa, Sa2, and Sa3 after expression in Escherichia coli. Protein expression and purification 51 9367812
2016 Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L. G3 (Bethesda, Md.) 47 27172213
2015 Phosphorylation of cohesin Rec11/SA3 by casein kinase 1 promotes homologous recombination by assembling the meiotic chromosome axis. Developmental cell 46 25579976
2015 Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation. PLoS genetics 46 25993311
2015 STAG3 truncating variant as the cause of primary ovarian insufficiency. European journal of human genetics : EJHG 46 26059840
2020 STAG3 homozygous missense variant causes primary ovarian insufficiency and male non-obstructive azoospermia. Molecular human reproduction 38 32634216
2017 Whole-exome sequencing identifies a homozygous donor splice-site mutation in STAG3 that causes primary ovarian insufficiency. Clinical genetics 37 28393351
2019 Novel STAG3 mutations in a Caucasian family with primary ovarian insufficiency. Molecular genetics and genomics : MGG 31 31363903
2005 Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6. The Journal of biological chemistry 29 16236716
2018 Two rare loss-of-function variants in the STAG3 gene leading to primary ovarian insufficiency. European journal of medical genetics 25 30006057
2019 In-Frame Variants in STAG3 Gene Cause Premature Ovarian Insufficiency. Frontiers in genetics 23 31803224
2017 Stag3 regulates microtubule stability to maintain euploidy during mouse oocyte meiotic maturation. Oncotarget 21 27906670
2003 Degradation of polyvinyl alcohol by Sphingomonas sp. SA3 and its symbiote. Journal of industrial microbiology & biotechnology 21 12545389
2022 Novel STAG3 variant associated with primary ovarian insufficiency and non-obstructive azoospermia in an Iranian consanguineous family. Gene 19 35176428
2018 Studying meiotic cohesin in somatic cells reveals that Rec8-containing cohesin requires Stag3 to function and is regulated by Wapl and sororin. Journal of cell science 18 29724914
2013 E2f6-mediated repression of the meiotic Stag3 and Smc1β genes during early embryonic development requires Ezh2 and not the de novo methyltransferase Dnmt3b. Epigenetics 16 23880518
2023 METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3. Scientific reports 15 37828232
2006 Production of an antimicrobial substance against Cryptococcus neoformans by Paenibacillus brasilensis Sa3 isolated from the rhizosphere of Kalanchoe brasiliensis. Microbiological research 14 16790336
2021 A Long Contiguous Stretch of Homozygosity Disclosed a Novel STAG3 Biallelic Pathogenic Variant Causing Primary Ovarian Insufficiency: A Case Report and Review of the Literature. Genes 11 34828315
2020 The association of stromal antigen 3 (STAG3) sequence variations with spermatogenic impairment in the male Korean population. Asian journal of andrology 10 31115363
2001 Evaluation of the Stag3 gene and the synaptonemal complex in a rat model (as/as) for male infertility. Molecular reproduction and development 10 11599053
2021 Biallelic loss of function variants in STAG3 result in primary ovarian insufficiency. Reproductive biomedicine online 8 34497033
2018 Retinoic acid-induced CYP51 nuclear translocation promotes meiosis prophase I process and is correlated to the expression of REC8 and STAG3 in mice. Biology open 6 30420384
2017 Association of the common SNPs in RNF212, STAG3 and RFX2 gene with male infertility with azoospermia in Chinese population. European journal of obstetrics, gynecology, and reproductive biology 5 29277047
2001 Purification, crystallization and preliminary X-ray analysis of two crystal forms of ribonuclease Sa3. Acta crystallographica. Section D, Biological crystallography 5 11320322
2025 Novel STAG3 variant causes oligoasthenoteratozoospermia with high sperm aneuploidy rate. Journal of assisted reproduction and genetics 3 39932630
2024 The Role of Prophage ϕSa3 in the Adaption of Staphylococcus aureus ST398 Sublineages from Human to Animal Hosts. Antibiotics (Basel, Switzerland) 3 38391498
2021 Analysis of STAG3 variants in Chinese non-obstructive azoospermia patients with germ cell maturation arrest. Scientific reports 3 33980954
2022 New STAG3 gene variant as a cause of premature ovarian insufficiency. Revista colombiana de obstetricia y ginecologia 2 35503298
2015 [Rab23 enhances invasion of Sa3 cutaneous squamous cell carcinoma cells via up-regulating the expression of Rac1]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2 26648292
2024 Statistical modelling, optimization, and mechanistic exploration of novel ureolytic Enterobacter hormaechei IITISM-SA3 in cadmium immobilization under microbial inclusive and cell-free conditions through microbially induced calcite precipitation. Environmental pollution (Barking, Essex : 1987) 1 38554835
2011 Expression of scFv SA3 against hepatoma fused with enhanced green fluorescent protein and its targeted ability in vivo. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 1 22086009

Missed literature

Know a paper Affinage missed for STAG3? Flag it for the maintainers and the community.

No submissions yet.