Showing LDLRAD3 — LRAD3 is a alias.
LDLRAD3
Low-density lipoprotein receptor class A domain-containing protein 3 · UniProt Q86YD5
Audit flag: ungrounded claim
- Length
- 345 aa
- Mass
- 37.4 kDa
- Annotated
- 2026-06-13
18 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 18 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2017 | Circular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer. | World journal of gastroenterology | 160 | 29307994 |
| 2020 | LDLRAD3 is a receptor for Venezuelan equine encephalitis virus. | Nature | 137 | 33208938 |
| 2019 | Downregulation of circular RNA circ-LDLRAD3 suppresses pancreatic cancer progression through miR-137-3p/PTN axis. | Life sciences | 61 | 31521692 |
| 2021 | Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3. | Nature | 52 | 34646021 |
| 2021 | Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor. | Nature | 48 | 34646020 |
| 2011 | LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking. | The Journal of neuroscience : the official journal of the Society for Neuroscience | 41 | 21795536 |
| 2020 | Circular RNA circ-LDLRAD3 serves as an oncogene to promote non-small cell lung cancer progression by upregulating SLC1A5 through sponging miR-137. | RNA biology | 37 | 32658600 |
| 2022 | circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition. | Gut and liver | 21 | 35975639 |
| 2016 | Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3. | Biochemistry | 21 | 26854353 |
| 2021 | Circ-LDLRAD3 Enhances Cell Growth, Migration, and Invasion and Inhibits Apoptosis by Regulating MiR-224-5p/NRP2 Axis in Gastric Cancer. | Digestive diseases and sciences | 15 | 33389349 |
| 2023 | Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice. | Cell reports | 13 | 37556325 |
| 2023 | Expression status of circ-SMARCA5, circ-NOL10, circ-LDLRAD3, and circ-RHOT1 in patients with colorectal cancer. | Scientific reports | 10 | 37587156 |
| 2022 | circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway. | Journal of healthcare engineering | 3 | 35035814 |
| 2024 | Circular RNA LDLRAD3 promotes gastric cancer progression by upregulating COL4A5 through sponging miR-h37. | Journal of the Chinese Medical Association : JCMA | 1 | 39161132 |
| 2026 | Transcriptomic and experimental validation identifies SOX6 and LDLRAD3 as key factors in vascular dementia. | The journals of gerontology. Series A, Biological sciences and medical sciences | 0 | 41344818 |
| 2025 | Chemically Synthesized LRAD3-D1 Interacts with N-Terminal Domain of SARS-CoV-2 Spike Protein. | Chembiochem : a European journal of chemical biology | 0 | 40583129 |
| 2024 | Circ-LDLRAD3/miR-655-3p/MAPK1 axis enhances cell migration and invasion in papillary thyroid carcinoma. | Cellular and molecular biology (Noisy-le-Grand, France) | 0 | 38430029 |
| 2023 | Retracted: circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway. | Journal of healthcare engineering | 0 | 37886338 |
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