IMPACT
Protein IMPACT · UniProt Q9P2X3
- Length
- 320 aa
- Mass
- 36.5 kDa
- Annotated
- 2026-06-10
100 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 100 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2002 | Stats: transcriptional control and biological impact. | Nature reviews. Molecular cell biology | 2625 | 12209125 |
| 2009 | SNPs: impact on gene function and phenotype. | Methods in molecular biology (Clifton, N.J.) | 433 | 19768584 |
| 2014 | RNA-seq: impact of RNA degradation on transcript quantification. | BMC biology | 365 | 24885439 |
| 2003 | Impact of aging on DNA methylation. | Ageing research reviews | 315 | 12726774 |
| 2004 | The impact of the inflammatory response on coagulation. | Thrombosis research | 257 | 15507261 |
| 2010 | Berries: emerging impact on cardiovascular health. | Nutrition reviews | 227 | 20384847 |
| 2010 | The impact of fruit flavonoids on memory and cognition. | The British journal of nutrition | 211 | 20955649 |
| 2005 | MaxiK channel partners: physiological impact. | The Journal of physiology | 192 | 16239267 |
| 2005 | Sarcopenia of aging and its metabolic impact. | Current topics in developmental biology | 191 | 16124998 |
| 2014 | miRNA biogenesis: biological impact in the development of cancer. | Cancer biology & therapy | 189 | 25482951 |
| 2018 | Impact of miRNA in Atherosclerosis. | Arteriosclerosis, thrombosis, and vascular biology | 178 | 30354259 |
| 2012 | CXCR7 impact on CXCL12 biology and disease. | Trends in molecular medicine | 175 | 23153575 |
| 2012 | MicroRNAs and neurodegeneration: role and impact. | Trends in cell biology | 166 | 23026030 |
| 2014 | Impact of the obesity epidemic on cancer. | Annual review of medicine | 150 | 25423596 |
| 2014 | Hog1: 20 years of discovery and impact. | Science signaling | 148 | 25227612 |
| 2014 | Impact of MCP-1 in atherosclerosis. | Current pharmaceutical design | 144 | 24862889 |
| 2016 | The impact of transposable elements on mammalian development. | Development (Cambridge, England) | 137 | 27875251 |
| 2024 | Origins and impact of extrachromosomal DNA. | Nature | 133 | 39506150 |
| 2015 | Cathelicidin impact on inflammatory cells. | Central-European journal of immunology | 131 | 26557038 |
| 2019 | The impact of epigenetics on cardiovascular disease. | Biochemistry and cell biology = Biochimie et biologie cellulaire | 98 | 31112654 |
| 2019 | The Impact of Heterogeneity on Single-Cell Sequencing. | Frontiers in genetics | 90 | 30881372 |
| 2019 | Transcriptional Effects of Ozone and Impact on Airway Inflammation. | Frontiers in immunology | 90 | 31354743 |
| 2010 | Impact of prolactin receptor isoforms on reproduction. | Trends in endocrinology and metabolism: TEM | 87 | 20149678 |
| 2014 | The impact of PKR activation: from neurodegeneration to cancer. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | 85 | 24522206 |
| 2024 | Deciphering the impact of genomic variation on function. | Nature | 82 | 39232149 |
| 2009 | BTG/TOB factors impact deadenylases. | Trends in biochemical sciences | 82 | 19828319 |
| 2005 | Reporter gene imaging: potential impact on therapy. | Nuclear medicine and biology | 79 | 16243653 |
| 2022 | Small Drugs, Huge Impact: The Extraordinary Impact of Antisense Oligonucleotides in Research and Drug Development. | Molecules (Basel, Switzerland) | 76 | 35056851 |
| 2006 | Epididymal SPAM1 and its impact on sperm function. | Molecular and cellular endocrinology | 74 | 16420970 |
| 2022 | The multifaceted impact of complement on atherosclerosis. | Atherosclerosis | 70 | 35365353 |
| 2019 | Regulatory variants: from detection to predicting impact. | Briefings in bioinformatics | 70 | 29893792 |
| 2019 | Impact of Rhinovirus Infections in Children. | Viruses | 70 | 31195744 |
| 2019 | The Impact of Centromeres on Spatial Genome Architecture. | Trends in genetics : TIG | 70 | 31200946 |
| 2017 | Impact of glucocorticoid on neurogenesis. | Neural regeneration research | 68 | 28852377 |
| 2007 | Impact of the comet assay in radiobiology. | Mutation research | 65 | 18083062 |
| 2014 | Impact of soy isoflavones on the epigenome in cancer prevention. | Nutrients | 62 | 25322458 |
| 2019 | Systemic drugs with impact on osteoarthritis. | Drug metabolism reviews | 61 | 31726891 |
| 2019 | Methylation Dynamics of RASSF1A and Its Impact on Cancer. | Cancers | 59 | 31323949 |
| 2022 | Epigenetic features drastically impact CRISPR-Cas9 efficacy in plants. | Plant physiology | 57 | 35689624 |
| 2012 | The impact of curcumin on breast cancer. | Integrative biology : quantitative biosciences from nano to macro | 57 | 22772921 |
| 2014 | Clinical impact of H-Y alloimmunity. | Immunologic research | 55 | 24781195 |
| 2001 | Apoptosis and its clinical impact. | Head & neck | 55 | 11295816 |
| 2018 | Impact of curcumin on sirtuins: A review. | Journal of cellular biochemistry | 54 | 30145851 |
| 2020 | Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity. | The Biochemical journal | 53 | 33135724 |
| 2018 | The pericyte secretome: Potential impact on regeneration. | Biochimie | 50 | 29698670 |
| 2007 | Impact of tiny miRNAs on cancers. | World journal of gastroenterology | 50 | 17278213 |
| 2021 | DNA mechanics and its biological impact. | Journal of molecular biology | 48 | 33539885 |
| 2007 | Early nutrition: impact on epigenetics. | Forum of nutrition | 47 | 17684400 |
| 2022 | Impact of Endocrine Disruptors upon Non-Genetic Inheritance. | International journal of molecular sciences | 44 | 35328771 |
| 2009 | InvAluable junk: the cellular impact and function of Alu and B2 RNAs. | IUBMB life | 44 | 19621349 |
| 2015 | Impact of heparanase on renal fibrosis. | Journal of translational medicine | 42 | 26040666 |
| 2017 | Progress and impact of enzyme measurement standardization. | Clinical chemistry and laboratory medicine | 40 | 27718484 |
| 2023 | Impact of ferroptosis on preeclampsia: A review. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie | 38 | 37729725 |
| 2024 | Impact of NQO1 dysregulation in CNS disorders. | Journal of translational medicine | 37 | 38167027 |
| 2022 | Impact of Probiotics on Dairy Production Efficiency. | Frontiers in microbiology | 37 | 35756055 |
| 2011 | Bioluminescence and its impact on bioanalysis. | Annual review of analytical chemistry (Palo Alto, Calif.) | 36 | 21456969 |
| 2022 | Chemical modifications to mRNA nucleobases impact translation elongation and termination. | Biophysical chemistry | 35 | 35313212 |
| 2020 | Impact of CRISPR interference on strain development in biotechnology. | Biotechnology and applied biochemistry | 35 | 32064678 |
| 2019 | The Impact of Protein Architecture on Adaptive Evolution. | Molecular biology and evolution | 35 | 31147689 |
| 2012 | Protein glycosylation and its impact on biotechnology. | Advances in biochemical engineering/biotechnology | 35 | 21975953 |
| 2009 | Thrombophilia and its impact on pregnancy. | Thrombosis research | 35 | 19203641 |
| 2019 | Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease. | The Journal of clinical endocrinology and metabolism | 34 | 30844069 |
| 2018 | The impact of DNA methylation in Alphaproteobacteria. | Molecular microbiology | 33 | 29995343 |
| 2023 | Impact of curcumin on p38 MAPK: therapeutic implications. | Inflammopharmacology | 32 | 37498375 |
| 2023 | X chromosome dosage and the genetic impact across human tissues. | Genome medicine | 30 | 36978128 |
| 2020 | Nuclear Functions of TOR: Impact on Transcription and the Epigenome. | Genes | 29 | 32532005 |
| 2011 | Impact of endurance and ultraendurance exercise on DNA damage. | Annals of the New York Academy of Sciences | 29 | 21793846 |
| 2006 | Impact of RNA interference on gene networks. | Metabolic engineering | 29 | 16996764 |
| 2018 | The Impact of Pazopanib on the Cardiovascular System. | Journal of cardiovascular pharmacology and therapeutics | 28 | 29706106 |
| 2022 | Impact of Siglecs on autoimmune diseases. | Molecular aspects of medicine | 27 | 36055802 |
| 2019 | The Impact of Emerging Bioconjugation Chemistries on Radiopharmaceuticals. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | 27 | 30902878 |
| 2014 | p53: its mutations and their impact on transcription. | Sub-cellular biochemistry | 26 | 25201189 |
| 2023 | Polyoxometalates Impact as Anticancer Agents. | International journal of molecular sciences | 25 | 36902473 |
| 2017 | The impact of VDR expression and regulation in vivo. | The Journal of steroid biochemistry and molecular biology | 25 | 28602960 |
| 2023 | Exploring impact of recombination landscapes on breeding outcomes. | Proceedings of the National Academy of Sciences of the United States of America | 24 | 36972450 |
| 2021 | DNA methylation impact on Fabry disease. | Clinical epigenetics | 24 | 33531072 |
| 2018 | Glycans in nanomedicine, impact and perspectives. | Future medicinal chemistry | 24 | 30526037 |
| 2019 | MicroRNA-21 and its impact on signaling pathways in cervical cancer. | Oncology letters | 23 | 30867735 |
| 2019 | Nesprin-1 impact on tumorigenic cell phenotypes. | Molecular biology reports | 23 | 31741263 |
| 2014 | TTDA: big impact of a small protein. | Experimental cell research | 23 | 25016283 |
| 2011 | Resveratrol and its impact on aging and thyroid function. | Journal of endocrinological investigation | 23 | 21946130 |
| 2007 | The impact of autoimmunity on hepatocytes. | Seminars in liver disease | 23 | 17520514 |
| 2004 | The -omics era and its impact. | Archives of pathology & laboratory medicine | 22 | 15578876 |
| 2021 | The ciliary impact of nonciliary gene mutations. | Trends in cell biology | 21 | 34183231 |
| 2019 | Impact of p85α Alterations in Cancer. | Biomolecules | 21 | 30650664 |
| 2017 | Impact of Gravity on Thyroid Cells. | International journal of molecular sciences | 21 | 28471415 |
| 2009 | Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling. | Results and problems in cell differentiation | 21 | 19132322 |
| 2000 | The socioeconomic impact of vasculitis. | Current opinion in rheumatology | 21 | 10647950 |
| 2022 | Impact of Genome Reduction in Microsporidia. | Experientia supplementum (2012) | 20 | 35543997 |
| 2019 | Pathological mTOR mutations impact cortical development. | Human molecular genetics | 20 | 30789219 |
| 2017 | Impact of X-irradiation on microglia. | Glia | 20 | 29024033 |
| 2011 | Metabolic impact of glucagon deficiency. | Diabetes, obesity & metabolism | 20 | 21824269 |
| 2024 | Research Coproduction: An Underused Pathway to Impact. | International journal of health policy and management | 19 | 39099499 |
| 2023 | Impact of delayed PBMC processing on functional and genomic assays. | Journal of immunological methods | 19 | 37353001 |
| 2021 | The impact of epigenetic information on genome evolution. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 19 | 33866804 |
| 2020 | The Impact of Cand1 in Prostate Cancer. | Cancers | 18 | 32059441 |
| 2017 | Impact of Phytochemicals and Dietary Patterns on Epigenome and Cancer. | Nutrition and cancer | 18 | 28094554 |
| 2003 | Epibatidine: impact on nicotinic receptor research. | Cellular and molecular neurobiology | 18 | 12825833 |
| 2019 | The impact of aneuploidy on cellular homeostasis. | Free radical research | 17 | 31117839 |
| 2015 | Impact of TRIM5α in vivo. | AIDS (London, England) | 17 | 26372380 |
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