- Length
- 340 aa
- Mass
- 35.8 kDa
- Annotated
- 2026-06-14
51 papers in source corpus
Mechanistic narrative
Synthesis pass · prose summary of the discoveries below
No mechanistic discoveries found in literature.
Mechanism profile
Synthesis pass · controlled-vocabulary classification · explore literature graph →
No controlled-vocabulary terms were assigned to this entry.
Source papers
Stage 0 corpus · 51 papers · ranked by NIH iCite citations
| Year | Title | Journal | Citations | PMID |
|---|---|---|---|---|
| 2008 | Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. | Nature structural & molecular biology | 199 | 18488039 |
| 2011 | Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. | Nature | 135 | 21460838 |
| 2016 | Genome-wide DNA Methylation Changes in a Mouse Model of Infection-Mediated Neurodevelopmental Disorders. | Biological psychiatry | 121 | 27769567 |
| 2000 | Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma. | Proceedings of the National Academy of Sciences of the United States of America | 86 | 10984508 |
| 1999 | Coexpression of transcripts encoding EPHB receptor protein tyrosine kinases and their ephrin-B ligands in human small cell lung carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research | 79 | 10037197 |
| 2011 | Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism. | Molecular autism | 76 | 21859478 |
| 1999 | High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas. | Clinical cancer research : an official journal of the American Association for Cancer Research | 74 | 10389937 |
| 2010 | De novo expression of EphA2 in osteosarcoma modulates activation of the mitogenic signalling pathway. | Histopathology | 58 | 21166698 |
| 2014 | Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization. | Journal of molecular neuroscience : MN | 55 | 25027557 |
| 2003 | Mouse ephrinB3 augments T-cell signaling and responses to T-cell receptor ligation. | The Journal of biological chemistry | 48 | 13679370 |
| 2019 | Pituitary Transcriptomic Study Reveals the Differential Regulation of lncRNAs and mRNAs Related to Prolificacy in Different FecB Genotyping Sheep. | Genes | 46 | 30781725 |
| 2004 | Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research | 46 | 15355914 |
| 2014 | Identification of molecular pathways facilitating glioma cell invasion in situ. | PloS one | 40 | 25365423 |
| 2019 | Sonic hedgehog pathway activation is associated with cetuximab resistance and EPHB3 receptor induction in colorectal cancer. | Theranostics | 34 | 31149041 |
| 2022 | Runs of Homozygosity Revealed Reproductive Traits of Hu Sheep. | Genes | 32 | 36292733 |
| 2012 | Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall. | Cancer cell international | 24 | 22995409 |
| 2001 | Association among EPHB2, TrkA, and MYCN expression in low-stage neuroblastomas. | Medical and pediatric oncology | 24 | 11464911 |
| 2012 | 790 Kb microduplication in chromosome band 17p13.1 associated with intellectual disability, afebrile seizures, dysmorphic features, diabetes, and hypothyroidism. | European journal of medical genetics | 20 | 22365944 |
| 2022 | Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer. | Cancers | 17 | 35565468 |
| 2019 | The Transcription Factor LHX1 Regulates the Survival and Directed Migration of POA-derived Cortical Interneurons. | Cerebral cortex (New York, N.Y. : 1991) | 17 | 29912395 |
| 2006 | Comparative integromics on Ephrin family. | Oncology reports | 17 | 16596216 |
| 2016 | Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure. | American journal of physiology. Heart and circulatory physiology | 16 | 26851246 |
| 2010 | 17p13.1 microdeletion involving the TP53 gene in a boy presenting with mental retardation but no tumor. | American journal of medical genetics. Part A | 16 | 20425836 |
| 2007 | De novo identification of MIZ-1 (ZBTB17) encoding a MYC-interacting zinc-finger protein as a new favorable neuroblastoma gene. | Clinical cancer research : an official journal of the American Association for Cancer Research | 16 | 17947461 |
| 1997 | cDNA cloning, chromosomal localization, and expression pattern of EPLG8, a new member of the EPLG gene family encoding ligands of EPH-related protein-tyrosine kinase receptors. | Genomics | 16 | 9126477 |
| 2013 | Destabilization of MYC/MYCN by the mitochondrial inhibitors, metaiodobenzylguanidine, metformin and phenformin. | International journal of molecular medicine | 15 | 24190252 |
| 2009 | High level MycN expression in non-MYCN amplified neuroblastoma is induced by the combination treatment nutlin-3 and doxorubicin and enhances chemosensitivity. | Oncology reports | 14 | 19885598 |
| 2016 | The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility. | Scientific reports | 13 | 27941904 |
| 2016 | Ephrin Bs and canonical Reelin signalling. | Nature | 12 | 27882975 |
| 2014 | Neurodevelopmental delays and macrocephaly in 17p13.1 microduplication syndrome. | American journal of medical genetics. Part A | 12 | 25123844 |
| 2022 | Glycoprotein attachment with host cell surface receptor ephrin B2 and B3 in mediating entry of nipah and hendra virus: a computational investigation. | Journal of chemical sciences (Bangalore, India) | 9 | 36465097 |
| 2017 | Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene. | Scientific reports | 8 | 28272517 |
| 2021 | Investigation of Key Signaling Pathways Associating miR-204 and Common Retinopathies. | BioMed research international | 7 | 34646884 |
| 2020 | Transcriptomic profile of Pea3 family members reveal regulatory codes for axon outgrowth and neuronal connection specificity. | Scientific reports | 7 | 33097800 |
| 2025 | Interpretable machine learning-guided single-cell mapping deciphers multi-lineage pancreatic dysregulation in type 2 diabetes. | Cardiovascular diabetology | 6 | 40707916 |
| 2015 | Genome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways for gastric adenocarcinoma. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine | 6 | 25687184 |
| 2024 | Structure-guided mutagenesis of Henipavirus receptor-binding proteins reveals molecular determinants of receptor usage and antibody-binding epitopes. | Journal of virology | 4 | 38426726 |
| 2023 | Evaluation of the interaction between potent small molecules against the Nipah virus Glycoprotein in Malaysia and Bangladesh strains, accompanied by the human Ephrin-B2 and Ephrin-B3 receptors; a simulation approach. | Molecular diversity | 4 | 36808582 |
| 2023 | Integrated analysis of RNA-seq in hepatocellular carcinoma reveals competing endogenous RNA network composed of circRNA, lncRNA, and mRNA. | Medicine | 4 | 36827016 |
| 2018 | Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism. | Scientific reports | 4 | 30262919 |
| 2025 | The alternatively spliced diacylglycerol kinase gamma-Δ exon13 transcript generated under hypoxia promotes glioblastoma progression. | Oncology research | 3 | 40296900 |
| 2025 | EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder. | Movement disorders : official journal of the Movement Disorder Society | 3 | 40401490 |
| 2021 | Activation of spinal ephrin-B3/EphBs signaling induces hyperalgesia through a PLP-mediated mechanism. | Fundamental & clinical pharmacology | 3 | 34904278 |
| 2023 | Ephrin B3 exacerbates colitis and colitis-associated colorectal cancer. | Biochemical pharmacology | 2 | 38142837 |
| 2025 | Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles. | MedComm | 1 | 41164797 |
| 2026 | Epigenetic mediators of diet and lifestyle and insulin resistance. | Genes & nutrition | 0 | 41580603 |
| 2026 | In silico characterization of G protein-host receptor interactions in Bangladesh Nipah virus mutants toward therapeutic target identification. | In silico pharmacology | 0 | 41613644 |
| 2026 | Autoencoder Denoising for Network-Based Spatial Transcriptomics Data with Applications for Cell Signaling Estimation. | Complex networks & their applications. International Conference on Complex Networks and Their Applications | 0 | 42181748 |
| 2025 | Ephrin B3 drives tumorigenesis and inflammation in cutaneous squamous cell carcinoma. | Medical oncology (Northwood, London, England) | 0 | 40711642 |
| 2025 | Germline Variant Call Accuracy in Whole Genome Sequence Data from Canine Formalin-Fixed Paraffin-Embedded Tissue Samples. | Genes | 0 | 41300821 |
| 2023 | Structure guided mutagenesis of Henipavirus Receptor Binding Proteins reveals molecular determinants of receptor usage and antibody binding epitopes. | bioRxiv : the preprint server for biology | 0 | 38045373 |
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